User profiles for Leah F. Cabo

Leah F. Cabo

PhD Student, University of Pittsburgh
Verified email at pitt.edu
Cited by 44

[HTML][HTML] A transcriptional network required for bradyzoite development in Toxoplasma gondii is dispensable for recrudescent disease

…, MD Massmann, KG Sharp, LF Cabo… - Nature …, 2023 - nature.com
Identification of regulators of Toxoplasma gondii bradyzoite development and cyst formation
is the most direct way to address the importance of parasite development in long-term …

Toxoplasma gondii GRA28 Is Required for Placenta-Specific Induction of the Regulatory Chemokine CCL22 in Human and Mouse

…, SE Ander, RS Coombs, HS Alrubaye, LF Cabo… - MBio, 2021 - Am Soc Microbiol
Toxoplasma gondii is an intracellular protozoan pathogen of humans that can cross the
placenta and result in adverse pregnancy outcomes and long-term birth defects. The …

Spatially explicit depiction of a floral epiphytic bacterial community reveals role for environmental filtering within petals

…, M Rebolleda‐Gómez, K Butela, LF Cabo… - …, 2021 - Wiley Online Library
The microbiome of flowers (anthosphere) is an understudied compartment of the plant
microbiome. Within the flower, petals represent a heterogeneous environment for microbes in …

Streptococcus pneumoniae secretion chaperones PrsA, SlrA, and HtrA are required for competence, antibiotic resistance, colonization, and invasive disease

JL George, C Agbavor, LF Cabo… - Infection and …, 2024 - Am Soc Microbiol
Streptococcus pneumoniae is a Gram-positive bacterium and a significant health threat with
the populations most at risk being children, the elderly, and the immuno-compromised. To …

[HTML][HTML] Toxoplasma gondii mitochondrial association factor 1b interactome reveals novel binding partners including Ral GTPase accelerating protein α1

…, ML Jenkins, TB Hill, ML Blank, LF Cabo… - Journal of Biological …, 2024 - ASBMB
The intracellular parasite, Toxoplasma gondii, has developed sophisticated molecular strategies
to subvert host processes and promote growth and survival. During infection, T. gondii …

[HTML][HTML] Heme-induced genes facilitate endosymbiont (Sodalis glossinidius) colonization of the tsetse fly (Glossina morsitans) midgut

…, JD Scheutzow, R Farsin, LF Cabo… - PLOS Neglected …, 2022 - journals.plos.org
Tsetse flies (Glossina spp.) feed exclusively on vertebrate blood. After a blood meal, the
enteric endosymbiont Sodalis glossinidius is exposed to various environmental stressors …

[HTML][HTML] Thermal stress responses of Sodalis glossinidius, an indigenous bacterial symbiont of hematophagous tsetse flies

…, S D'Souza, PJ Somers, LF Cabo… - PLoS neglected …, 2019 - journals.plos.org
Tsetse flies (Diptera: Glossinidae) house a taxonomically diverse microbiota that includes
environmentally acquired bacteria, maternally transmitted symbiotic bacteria, and pathogenic …

A transcriptional network required for Toxoplasma gondii tissue cyst formation is dispensable for long-term persistence

SS Borrelli, SM Reilly, KG Sharp, LF Cabo… - bioRxiv, 2022 - biorxiv.org
Cyst formation is a key feature of the T. gondii life cycle but the genetic networks that drive
this process are not yet fully characterized. To identify new components of this network, we …

[PDF][PDF] Toxoplasma gondii GRA28 is required for specific induction of the regulatory chemokine CCL22 in human and mouse cells

…, SE Ander, RS Coombs, HI Alrubaye, LF Cabo… - BioRxiv, 2020 - scholar.archive.org
Toxoplasma gondii is an intracellular protozoan pathogen of humans that causes severe
disease in immunocompromised patients and in the developing fetus. T. gondii specifically …

Human trophoblast stem cells can be used to model placental susceptibility to Toxoplasma gondii and highlight the critical importance of the trophoblast cell surface …

RJ da Silva, LF Cabo, JL George, LA Cahoon, L Yang… - bioRxiv, 2023 - biorxiv.org
The placenta is a critical barrier against viral, bacterial, and eukaryotic pathogens. For most
teratogenic pathogens, the precise molecular mechanisms of placental resistance are still …