Saturated fat is more metabolically harmful for the human liver than unsaturated fat or simple sugars

…, A Gastaldelli, K Clement, L Hodson… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE Nonalcoholic fatty liver disease (ie, increased intrahepatic triglyceride [IHTG]
content), predisposes to type 2 diabetes and cardiovascular disease. Adipose tissue lipolysis …

Downregulation of adipose tissue fatty acid trafficking in obesity: a driver for ectopic fat deposition?

SE McQuaid, L Hodson, MJ Neville, AL Dennis… - Diabetes, 2011 - Am Diabetes Assoc
OBJECTIVE Lipotoxicity and ectopic fat deposition reduce insulin signaling. It is not clear
whether excess fat deposition in nonadipose tissue arises from excessive fatty acid delivery …

Fatty acid composition of adipose tissue and blood in humans and its use as a biomarker of dietary intake

L Hodson, CM Skeaff, BA Fielding - Progress in lipid research, 2008 - Elsevier
Accurate assessment of fat intake is essential to examine the relationships between diet
and disease risk but the process of estimating individual intakes of fat quality by dietary …

The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state

L Hodson, PJ Gunn - Nature Reviews Endocrinology, 2019 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is an increasing global public health burden. NAFLD
is strongly associated with type 2 diabetes mellitus, obesity and cardiovascular disease …

Dietary carbohydrates and fats in nonalcoholic fatty liver disease

H Yki-Järvinen, PK Luukkonen, L Hodson… - Nature reviews …, 2021 - nature.com
The global prevalence of nonalcoholic fatty liver disease (NAFLD) has dramatically
increased in parallel with the epidemic of obesity. Controversy has emerged around dietary …

Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management

T Marjot, A Moolla, JF Cobbold, L Hodson… - Endocrine …, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It is …

[HTML][HTML] Dietary-induced changes in fatty acid composition of human plasma, platelet, and erythrocyte lipids follow a similar time course

CM Skeaff, L Hodson, JE McKenzie - The Journal of nutrition, 2006 - Elsevier
The dietary-induced changes in the fatty acid composition of plasma, platelet, and erythrocyte
lipids were measured as a function of time. Healthy adults consumed a diet rich in …

[BOOK][B] Essentials of Human Nutrition 6e

J Mann, S Truswell, L Hodson - 2023 - books.google.com
… Jim Mann and Stewart Truswell were delighted that Leanne Hodson agreed to join them
as an editor of the sixth edition. We hope that all readers of our book will find it useful in their …

[HTML][HTML] The influence of dietary fat on liver fat accumulation

CJ Green, L Hodson - Nutrients, 2014 - mdpi.com
Obesity is a known risk factor for the development of non-alcoholic fatty liver disease (NAFLD);
however, it has been suggested that dietary fat, both amount and composition, may play a …

Metabolic signatures of human adipose tissue hypoxia in obesity

L Hodson, SM Humphreys, F Karpe, KN Frayn - Diabetes, 2013 - Am Diabetes Assoc
Adipose tissue (AT) hypoxia has been proposed as the cause of obesity-related AT dysfunction,
moving the tissue toward a proinflammatory phenotype. In humans, AT oxygenation has …