Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK (…

Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention 1 , 2 , much remains unknown about ZIKV disease …

Metagenomic sequencing has the potential to transform microbial detection and
characterization, but new tools are needed to improve its sensitivity. Here we present CATCH, a …

Metagenomic sequencing has the potential to transform microbial detection and
characterization, but new tools are needed to improve its sensitivity. We developed CATCH (Compact …

Despite great attention given to the recent Zika virus (ZIKV) epidemic in the Americas, much
remains unknown about its epidemiology and evolution, in part due to a lack of genomic data…

Background Studies examining the association between in utero Zika virus (ZIKV) exposure
and child neurodevelopmental outcomes have produced varied results. Methods We aimed …

Background Genetic risk factors for dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS)
and dengue fever (DF) are limited, in particular there are sparse data on genetic risk …

Although the recent Zika virus (ZIKV) epidemic in the Americas and its link to birth defects
have attracted a great deal of attention1, 2, much remains unknown about ZIKV disease …

The recent Zika virus (ZIKV) epidemic swept across Latin America and the Caribbean,
where dengue virus (DENV) is endemic. The antigenic similarities of these closely related …

Introduction We assessed HIV drug resistance (DR) in individuals failing ART (acquired DR,
ADR) and in ART-naïve individuals (pre-ART DR, PDR) in Honduras, after 10 years of …