Toxoplasma gondii chronic infection in rodent secondary hosts has been reported to lead to
a loss of innate, hard-wired fear toward cats, its primary host. However the generality of this …

10.7554/eLife.34870.001 TET enzymes convert 5-methylcytosine to 5-hydroxymethylcytosine
and higher oxidized derivatives. TETs stably associate with and are post-translationally …

CRISPR/Cas technologies have transformed our ability to add functionality to the genome
by knock-in of payload via homology-directed repair (HDR). However, a systematic and …

Developmental signaling molecules are used for cell fate determination, and understanding
how their combinatorial effects produce the variety of cell types in multicellular organisms is …

In early female embryos X-chromosome inactivation occurs concomitant with up regulation
of the non-coding RNA, Xist, on the future inactive X-chromosome. Up regulation of Xist and …

In placental mammals, dosage compensation of the sex chromosomes isachieved through
inactivation of one X chromosome in female cells. This Xchromosome inactivation (XCI) …

All animals live in a microbe rich environment, with immense numbers of bacteria, archaea,
fungi and other eukaryotic microbes living in, on and around them. For some of these …

… x The analysis of RNA-seq data in Figure 2.7D was performed by Leeanne Goodrich. x The
mass spectrometry in Figure 2.7F was performed by Jenna Fernandez in the lab of Natalia …

Heterochromatin protein-1 (HP1) maintains condensed, stable heterochromatin domains
throughout interphase despite the weak binding and rapid exchange of HP1 within …

… Leeanne Goodrich and Betsy Martin also became fierce advocates for me, and really shaped
my growth as a scientist in the lab and as an individual outside of the lab. Since I became a …