User profiles for Leen Abraham

Leen Abraham

Research assistant
Verified email at unine.ch
Cited by 191

[HTML][HTML] A 19-isolate reference-quality global pangenome for the fungal wheat pathogen Zymoseptoria tritici

T Badet, U Oggenfuss, L Abraham, BA McDonald… - BMC biology, 2020 - Springer
Background The gene content of a species largely governs its ecological interactions and
adaptive potential. A species is therefore defined by both core genes shared between all …

A population-level invasion by transposable elements triggers genome expansion in a fungal pathogen

…, T Wicker, FE Hartmann, NK Singh, L Abraham… - Elife, 2021 - elifesciences.org
Genome evolution is driven by the activity of transposable elements (TEs). The spread of
TEs can have deleterious effects including the destabilization of genome integrity and …

[HTML][HTML] Rapid sequence evolution driven by transposable elements at a virulence locus in a fungal wheat pathogen

NK Singh, T Badet, L Abraham, D Croll - BMC genomics, 2021 - Springer
Background Plant pathogens cause substantial crop losses in agriculture production and
threaten food security. Plants evolved the ability to recognize virulence factors and pathogens …

[HTML][HTML] Genome-wide expression QTL mapping reveals the highly dynamic regulatory landscape of a major wheat pathogen

LN Abraham, D Croll - BMC biology, 2023 - Springer
Background In agricultural ecosystems, outbreaks of diseases are frequent and pose a
significant threat to food security. A successful pathogen undergoes a complex and well-timed …

Population-level transposable element expression dynamics influence trait evolution in a fungal crop pathogen

LN Abraham, U Oggenfuss, D Croll - Mbio, 2024 - Am Soc Microbiol
The rapid adaptive evolution of microbes is driven by strong selection pressure acting on
genetic variation. How adaptive genetic variation is generated within species and how such …

Improved gene annotation of the fungal wheat pathogen Zymoseptoria tritici based on combined Iso-Seq and RNA-Seq evidence

…, Y Petit, A Genissel, C Delude, A Feurtey, LN Abraham… - bioRxiv, 2023 - biorxiv.org
Despite large omics datasets, the establishment of a reliable gene annotation is still challenging
for eukaryotic genomes. Here, we used the reference genome of the major fungal wheat …

A population-level invasion by transposable elements in a fungal pathogen

…, T Wicker, FE Hartmann, NK Singh, LN Abraham… - BioRxiv, 2020 - biorxiv.org
Transposable elements (TEs) are key drivers of adaptive evolution within species. Yet, the
propagation of TEs across the genome can be highly deleterious and ultimately lead to …

Optimization of parameters to improve transformation efficiency of elephant foot yam (Amorphophallus paeoniifolius (Dennst.) Nicolson

LN Abraham, S Kamala, J Sreekumar, T Makeshkumar - 3 Biotech, 2021 - Springer
Elephant foot yam (Amorphophallus paeoniifolius (Dennst.) Nicolson), is an important edible
tropical tuber crop, belonging to the family Araceae. Corms produced by this plant is very …

[HTML][HTML] Genome-wide association mapping reveals genes underlying population-level metabolome diversity in a fungal crop pathogen

NK Singh, SM Tralamazza, LN Abraham, G Glauser… - BMC biology, 2022 - Springer
Background Fungi produce a wide range of specialized metabolites (SMs) involved in biotic
interactions. Pathways for the production of SMs are often encoded in clusters of tightly …

Genome Evolution in Fungal Plant Pathogens: From Populations to Kingdom-Wide Dynamics

…, G Puccetti, HM Glad, LN Abraham… - Evolution of Fungi and …, 2023 - Springer
Plant pathogenic fungi have emerged as major concerns for plant health in agriculture and
occupy important niches in natural ecosystems. Pathogen species are often highly diverse …