User profiles for Leena B. Mithal

Leena B. Mithal

Northwestern University Feinberg School of Medicine; Lurie Children's
Verified email at luriechildrens.org
Cited by 1566

Placental pathology in COVID-19

ED Shanes, LB Mithal, S Otero, HA Azad… - American journal of …, 2020 - academic.oup.com
Objectives To describe histopathologic findings in the placentas of women with coronavirus
disease 2019 (COVID-19) during pregnancy. Methods Pregnant women with COVID-19 …

Cord blood antibodies following maternal coronavirus disease 2019 vaccination during pregnancy

LB Mithal, S Otero, ED Shanes, JA Goldstein… - American Journal of …, 2021 - ajog.org
… The average maternal to infant IgG transfer ratio was 1.0±0.6 (Figure, B), however, an
increased latency from vaccination to delivery (weeks) was associated with an increased …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination in pregnancy: measures of immunity and placental histopathology

ED Shanes, S Otero, LB Mithal… - Obstetrics & …, 2021 - journals.lww.com
METHODS The study methods have been described previously and were approved by the
Northwestern University institutional review board. 7, 15 We report results from patients who …

Chorioamnionitis and risk for maternal and neonatal sepsis: a systematic review and meta-analysis

…, LA Taylor, JA Goldstein, LB Mithal… - Obstetrics & …, 2021 - journals.lww.com
OBJECTIVE: To estimate the risk of maternal and neonatal sepsis associated with
chorioamnionitis. DATA SOURCES: PubMed, BIOSIS, and ClinicalTrials. gov databases were …

SARS-CoV-2 infection in infants less than 90 days old

LB Mithal, KZ Machut, WJ Muller, LK Kociolek - The Journal of pediatrics, 2020 - Elsevier
This is a single-center US case series of 18 infants <90 days old who tested positive for severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). These infants had a mild febrile …

[HTML][HTML] Cord blood acute phase reactants predict early onset neonatal sepsis in preterm infants

LB Mithal, HL Palac, R Yogev, LM Ernst, KK Mestan - PLOS one, 2017 - journals.plos.org
Background Early onset sepsis (EOS) is a major cause of morbidity and mortality in preterm
infants, yet diagnosis remains inadequate resulting in missed cases or prolonged empiric …

Mechanisms and modulation of sepsis-induced immune dysfunction in children

LB Mithal, M Arshad, LR Swigart, A Khanolkar… - Pediatric …, 2022 - nature.com
Immunologic responses during sepsis vary significantly among patients and evolve over the
course of illness. Sepsis has a direct impact on the immune system due to adverse …

Placental pathology after SARS-CoV-2 infection in the pre-variant of concern, alpha/gamma, delta, or omicron eras

…, AS Willnow, EA Ozer, LB Mithal… - … Journal of Surgical …, 2023 - journals.sagepub.com
Objectives. The goal of this study is to describe placental pathology after infection with SARS-CoV-2
before the predominance of variants of concern (pre-VOC) and during eras of …

Maternal antibody response and transplacental transfer following severe acute respiratory syndrome coronavirus 2 infection or vaccination in pregnancy

…, A Sakowicz, JA Goldstein, LB Mithal - Clinical Infectious …, 2023 - academic.oup.com
Leena B Mithal Leena B Mithal … Mathematical models of maternal IgG level (A) across
severity categories and (B) vaccination versus symptomatic SARS-CoV-2 infection. Blue = …

Low-level SARS-CoV-2 viremia coincident with COVID placentitis and stillbirth

LB Mithal, S Otero, LM Simons, JF Hultquist, ES Miller… - Placenta, 2022 - Elsevier
SARS-CoV-2 infection in pregnancy and COVID placentitis are associated with an increased
risk of stillbirth. We sought to investigate the presence of maternal viremia in people with …