Gene set analysis (GSA) is used to elucidate genome-wide data, in particular transcriptome
data. A multitude of methods have been proposed for this step of the analysis, and many of …

Pdgfra+ oligodendrocyte precursor cells (OPCs) arise in distinct specification waves during
embryogenesis in the central nervous system (CNS). It is unclear whether there is a …

Background Succinate dehydrogenase (SDH) is a mitochondrial metabolic enzyme complex
involved in both the electron transport chain and the citric acid cycle. SDH mutations …

Skeletal myocytes are metabolically active and susceptible to insulin resistance and are
thus implicated in type 2 diabetes (T2D). This complex disease involves systemic metabolic …

Background To understand cardiac and skeletal muscle function, it is important to define and
explore their molecular constituents and also to identify similarities and differences in the …

The growing prevalence of metabolic diseases, such as obesity and diabetes, are putting a
high strain on global healthcare systems as well as increasing the demand for efficient …

Background Skeletal muscle is one of the primary tissues involved in the development of
type 2 diabetes (T2D). The close association between obesity and T2D makes it difficult to …

Abstract Analysis of large data sets using computational and mathematical tools have become
a central part of biological sciences. Large amounts of data are being generated each …

Diapause is a deep resting stage facilitating temporal avoidance of unfavourable environmental
conditions, and is used by many insects to adapt their life cycle to seasonal variation. …

Dietary polyunsaturated fatty acids (PUFA) are suggested to modulate immune function, but
the effects of dietary fatty acids composition on gene expression patterns in immune organs …