Tissue-resident CD8+ T cells drive compartmentalized and chronic autoimmune damage against CNS neurons

D Frieser, A Pignata, L Khajavi, D Shlesinger… - Science translational …, 2022 - science.org
The mechanisms underlying the chronicity of autoimmune diseases of the central nervous
system (CNS) are largely unknown. In particular, it is unclear whether tissue-resident memory …

[HTML][HTML] MeCP2-E1 isoform is a dynamically expressed, weakly DNA-bound protein with different protein and DNA interactions compared to MeCP2-E2

A Martínez de Paz, L Khajavi, H Martin… - Epigenetics & …, 2019 - Springer
Background MeCP2—a chromatin-binding protein associated with Rett syndrome—has two
main isoforms, MeCP2-E1 and MeCP2-E2, differing in a few N-terminal amino acid residues…

Influenza vaccination induces autoimmunity against orexinergic neurons in a mouse model for narcolepsy

R Bernard-Valnet, D Frieser, XH Nguyen, L Khajavi… - Brain, 2022 - academic.oup.com
Narcolepsy with cataplexy or narcolepsy type 1 is a disabling chronic sleep disorder resulting
from the destruction of orexinergic neurons in the hypothalamus. The tight association of …

Dietary antioxidants and fibre intake and depressive symptoms in Iranian adolescent girls

…, S Arekhi, A Naseri, A Ziaee, L Khajavi… - Public health …, 2021 - cambridge.org
Objective:To investigate the cross-sectional association between dietary intakes of antioxidants
and fibre and depressive symptoms among Iranian adolescent girls.Design:A cross-…

[HTML][HTML] The transcriptomics profiling of blood CD4 and CD8 T-cells in narcolepsy type I

L Khajavi, XH Nguyen, C Queriault, M Chabod… - Frontiers in …, 2023 - frontiersin.org
Background Narcolepsy Type I (NT1) is a rare, life-long sleep disorder arising as a
consequence of the extensive destruction of orexin-producing hypothalamic neurons. The …

A variant in CYP2R1 predicts circulating vitamin D levels after supplementation with high‐dose of vitamin D in healthy adolescent girls

…, H Esmaeily, SJ Mirmousavi, L Khajavi… - Journal of Cellular …, 2019 - Wiley Online Library
Aim The determinants of serum vitamin D seems to be the environmental factors (dietary
and supplementary intake and exposure to ultraviolet light) and genetic factors. We aimed to …

Association of dysglycemia with mortality in children receiving parenteral nutrition in pediatric intensive care unit

L Khajavi, G Khademi, M Mehramiz… - The Turkish journal of …, 2018 - turkjpediatr.org
Khajavi L, Khademi G, Mehramiz M, Norouzy A, Safarian M. Association of dysglycemia with
mortality in children receiving parenteral nutrition in pediatric intensive care unit. Turk J …

[PDF][PDF] Nutritional status of pediatric patients with cancer in Iran: A single center study

L Khajavi, H Farhangi, S Movahhed… - مجله ی خون و سرطان ایران, 2020‎ - ijbc.ir
Background: As children have a higher metabolic rate and higher calorie needs for growth,
they are more susceptible to nutritional depletion than adults. We aimed to assess the …

[PDF][PDF] Iranian Journal of Blood & Cancer

L Khajavi, H Farhangi, S Movahed, FN Salehkhani… - academia.edu
Background: As children have a higher metabolic rate and higher calorie needs for growth,
they are more susceptible to nutritional depletion than adults. We aimed to assess the …

[HTML][HTML] MeCP2 modulates gene expression pathways in astrocytes

DH Yasui, H Xu, KW Dunaway, JM LaSalle, LW Jin… - Molecular autism, 2013 - Springer
Background Mutations in MECP2 encoding methyl-CpG-binding protein 2 (MeCP2) cause
the X-linked neurodevelopmental disorder Rett syndrome. Rett syndrome patients exhibit …