Ancient human genomes suggest three ancestral populations for present-day Europeans

…, W Klitz, V Kučinskas, A Kushniarevich, L Laredj… - Nature, 2014 - nature.com
We sequenced the genomes of a ∼7,000-year-old farmer from Germany and eight ∼8,000-year-old
hunter-gatherers from Luxembourg and Sweden. We analysed these and other …

The molecular genetics of coenzyme Q biosynthesis in health and disease

LN Laredj, F Licitra, HM Puccio - Biochimie, 2014 - Elsevier
Coenzyme Q, or ubiquinone, is an endogenously synthesized lipid-soluble antioxidant that
plays a major role in the mitochondrial respiratory chain. Although extensively studied for …

[PDF][PDF] Cerebellar ataxia and coenzyme Q deficiency through loss of unorthodox kinase activity

JA Stefely, F Licitra, L Laredj, AG Reidenbach… - Molecular cell, 2016 - cell.com
The UbiB protein kinase-like (PKL) family is widespread, comprising one-quarter of microbial
PKLs and five human homologs, yet its biochemical activities remain obscure. COQ8A (…

The MTM1–UBQLN2–HSP complex mediates degradation of misfolded intermediate filaments in skeletal muscle

C Gavriilidis, L Laredj, R Solinhac, N Messaddeq… - Nature cell …, 2018 - nature.com
The ubiquitin proteasome system and autophagy are major protein turnover mechanisms in
muscle cells, which ensure stemness and muscle fibre maintenance. Muscle cells contain a …

Adeno-associated virus activates an innate immune response in normal human cells but not in osteosarcoma cells

LN Laredj, P Beard - Journal of virology, 2011 - Am Soc Microbiol
Adeno-associated virus (AAV) is a small, DNA-containing dependovirus with promising potential
as a gene delivery vehicle. Given the variety of applications of AAV-based vectors in the …

Growth of osteosarcoma cells in a three-dimensional bone-like matrix alters their susceptibility to adeno-associated virus

S Dey, L Laredj, K Damjanovic… - Journal of General …, 2014 - microbiologyresearch.org
Osteosarcoma cells U2OS are partially susceptible to adeno-associated virus (AAV)-2
infection, allowing efficient synthesis of Rep proteins and, in a low percentage of cells, capsid …

The Multiple Faces of Shahrazad: Leïla Sebbar and Waçiny Laredj

R van Leeuwen - The Thousand and One Nights and Twentieth-Century …, 2018 - brill.com
Laredj), … of Laredj’s novel Les ailes de la reine, which should be seen as an indictment of
the Islamist assault on modern culture and art. As in Leïla Sebbar’s Shérézade trilogy, in Laredj’…

[HTML][HTML] Inborn errors of immunity in Algerian children and adults: a single-center experience over a period of 13 years (2008–2021)

…, M Oussalah, N Benaissa, A Laredj… - Frontiers in …, 2022 - frontiersin.org
Background Inborn errors of immunity (IEI) predispose patients to various infectious and non-infectious
complications. Thanks to the development and expanding use of flow cytometry …

[HTML][HTML] Percutaneous Coronary Intervention for a Pregnant Woman with Acute ST Elevation Myocardial Infarction: A Case Report

F Boukerche, AA Ali, N Laredj, L Hammou - World Journal of …, 2020 - scirp.org
Acute myocardial infarction in women during childbearing age is rare. We report a case of a
40-year-old female patient with no history or cardiovascular risk factors, 24-week pregnant …

[PDF][PDF] Anatomical Study of Atriplex halimus L.(Guettaf) Growing under the Climatic Conditions of Biskra-Algeria

K Ounaissia, L Ailane, H Laredj, S Bennadja, D Smati - 2019 - researchgate.net
Atriplex halimus L. known as “Guettaf”(Amaranthaceae) is used in Algerian traditional medicine
to treat several diseases such as rheumatism and fever. The aim of this work is to study …