[HTML][HTML] Modulation of inflammatory responses by gastrointestinal Prevotella spp.–from associations to functional studies
Numerous studies have associated alterations in the gut microbiota composition with almost
every known inflammatory disease. However, proving the biological relevance of distinct …
every known inflammatory disease. However, proving the biological relevance of distinct …
[HTML][HTML] Perturbation of the gut microbiome by Prevotella spp. enhances host susceptibility to mucosal inflammation
…, TR Lesker, B Zhao, A Gronow, L Amend… - Mucosal …, 2021 - Elsevier
Diverse microbial signatures within the intestinal microbiota have been associated with
intestinal and systemic inflammatory diseases, but whether these candidate microbes actively …
intestinal and systemic inflammatory diseases, but whether these candidate microbes actively …
[PDF][PDF] Distinct polysaccharide utilization determines interspecies competition between intestinal Prevotella spp.
EJC Gálvez, A Iljazovic, L Amend, TR Lesker… - Cell Host & Microbe, 2020 - cell.com
Prevotella spp. are a dominant bacterial genus within the human gut. Multiple Prevotella spp.
co-exist in some individuals, particularly those consuming plant-based diets. Additionally, …
co-exist in some individuals, particularly those consuming plant-based diets. Additionally, …
[HTML][HTML] Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is expected to be the second most deadly
cancer by 2040, owing to the high incidence of metastatic disease and limited responses to …
cancer by 2040, owing to the high incidence of metastatic disease and limited responses to …
[PDF][PDF] Extension of the Segatella copri complex to 13 species with distinct large extrachromosomal elements and associations with host conditions
The Segatella copri (formerly Prevotella copri) complex (ScC) comprises taxa that are key
members of the human gut microbiome. It was previously described to contain four distinct …
members of the human gut microbiome. It was previously described to contain four distinct …
[HTML][HTML] Characterization of serum biomarkers and antibody responses against Prevotella spp. in preclinical and new-onset phase of rheumatic diseases
L Amend, BTP Gilbert, P Pelczar, M Böttcher… - Frontiers in Cellular …, 2023 - frontiersin.org
Introduction The characterization of the influence of the microbiota on the development and
drug responses during rheumatic diseases has intensified in recent years. The role of …
drug responses during rheumatic diseases has intensified in recent years. The role of …
A versatile genetic toolbox for Prevotella copri enables studying polysaccharide utilization systems
Prevotella copri is a prevalent inhabitant of the human gut and has been associated with
plant‐rich diet consumption and diverse health states. The underlying genetic basis of these …
plant‐rich diet consumption and diverse health states. The underlying genetic basis of these …
[HTML][HTML] Brief report: Assessment of mucosal barrier integrity using serological biomarkers in preclinical stages of rheumatoid arthritis
Background The pathogenesis of rheumatoid arthritis (RA) is believed to initiate at mucosal
sites. The so-called ‘mucosal origin hypothesis of RA’ postulates an increased intestinal …
sites. The so-called ‘mucosal origin hypothesis of RA’ postulates an increased intestinal …
[HTML][HTML] Distinct Microbial Taxa Are Associated with LDL-Cholesterol Reduction after 12 Weeks of Lactobacillus plantarum Intake in Mild Hypercholesterolemia …
Probiotic microbes such as Lactobacillus may reduce serum total cholesterol (TC) and low-density
lipoprotein (LDL) cholesterol. The objective of this study was to assess the effect of …
lipoprotein (LDL) cholesterol. The objective of this study was to assess the effect of …
[HTML][HTML] A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes
Objective Protein disulfide isomerases (PDIs) are oxidoreductases that are involved in
catalyzing the formation and rearrangement of disulfide bonds during protein folding. One of the …
catalyzing the formation and rearrangement of disulfide bonds during protein folding. One of the …