Comprehensive knowledge of the brain’s wiring diagram is fundamental for understanding
how the nervous system processes information at both local and global scales. However, with …

The mammalian cortex is a laminar structure containing many areas and cell types that are
densely interconnected in complex ways, and for which generalizable principles of …

Glioblastoma is an aggressive brain tumor that carries a poor prognosis. The tumor’s
molecular and cellular landscapes are complex, and their relationships to histologic features …

Although there have been major advances in elucidating the functional biology of the human
brain, relatively little is known of its cellular and molecular organization. Here we report a …

To provide a temporal framework for the genoarchitecture of brain development, we
generated in situ hybridization data for embryonic and postnatal mouse brain at seven …

To understand how the brain processes sensory information to guide behavior, we must know
how stimulus representations are transformed throughout the visual cortex. Here we report …

The Allen Mouse Brain Connectivity Atlas is a mesoscale whole brain axonal projection atlas
of the C57Bl/6J mouse brain. Anatomical trajectories throughout the brain were mapped …

The evolutionarily conserved default mode network (DMN) is a distributed set of brain regions
coactivated during resting states that is vulnerable to brain disorders. How disease affects …

Background Spatially mapped large scale gene expression databases enable quantitative
comparison of data measurements across genes, anatomy, and phenotype. In most ongoing …

A variety of Alzheimer's disease (AD) mouse models overexpress mutant forms of human
amyloid precursor protein (APP), producing high levels of amyloid β (Aβ) and forming plaques. …