2). For instance, in this setting with m= 10 and q= 10, IDA found 4, 4, 5, 1 and 2 true positives
for the five different networks, whereas Lasso found 1, 1, 0, 1 and 2 true positives and …

It has long been the dream of biologists to map gene expression at the single-cell level.
With such data one might track heterogeneous cell sub-populations, and infer regulatory …

The naked mole rat (Heterocephalus glaber) is a strictly subterranean, extraordinarily long-lived
eusocial mammal 1 . Although it is the size of a mouse, its maximum lifespan exceeds …

INTRODUCTION Metazoan development represents a big jump in complexity compared
with unicellular life in two aspects: cell-type differentiation and cell spatial organization. In …

A small molecule that safely mimics the ability of dietary restriction (DR) to delay age-related
diseases in laboratory animals is greatly sought after. We and others have shown that …

Mammals have extremely limited regenerative capabilities; however, axolotls are profoundly
regenerative and can replace entire limbs. The mechanisms underlying limb regeneration …

Cooperative games are those in which both agents share the same payoff structure. Value-based
reinforcement-learning algorithms, such as variants of Q-learning, have been applied …

Wnt signaling plays a critical role in embryonic development, and genetic aberrations in this
network have been broadly implicated in colorectal cancer. We find that the Wnt receptor …

We present a technique for computing approximately optimal solutions to stochastic resource
allocation problems modeled as Markov decision processes (MDPs). We exploit two key …

Background Mass spectrometry-based proteomics enables the global identification and
quantification of proteins and their posttranslational modifications in complex biological samples. …