User profiles for Leonie Kirszenblat

Leonie Kirszenblat

Queensland Brain Institute, The University of Queensland
Verified email at uq.edu.au
Cited by 886

A dynamic deep sleep stage in Drosophila

B Van Alphen, MHW Yap, L Kirszenblat… - Journal of …, 2013 - Soc Neuroscience
How might one determine whether simple animals such as flies sleep in stages? Sleep in
mammals is a dynamic process involving different stages of sleep intensity, and these are …

[PDF][PDF] Sleep restores behavioral plasticity to Drosophila mutants

S Dissel, V Angadi, L Kirszenblat, Y Suzuki, J Donlea… - Current Biology, 2015 - cell.com
Given the role that sleep plays in modulating plasticity, we hypothesized that increasing
sleep would restore memory to canonical memory mutants without specifically rescuing the …

The yin and yang of sleep and attention

L Kirszenblat, B van Swinderen - Trends in neurosciences, 2015 - cell.com
Sleep is not a single state, but a complex set of brain processes that supports several
physiological needs. Sleep deprivation is known to affect attention in many animals, suggesting …

[PDF][PDF] A paradoxical kind of sleep in Drosophila melanogaster

LAL Tainton-Heap, LC Kirszenblat, ET Notaras… - Current Biology, 2021 - cell.com
The dynamic nature of sleep in many animals suggests distinct stages that serve different
functions. Genetic sleep induction methods in animal models provide a powerful way to …

Closed-loop behavioral control increases coherence in the fly brain

AC Paulk, L Kirszenblat, Y Zhou… - Journal of …, 2015 - Soc Neuroscience
A crucial function of the brain is to be able to distinguish whether or not changes in the
environment are caused by one's own actions. Even the smallest brains appear to be capable of …

The two‐component histidine kinases DrkA and SlnA are required for in vivo growth in the human pathogen Penicillium marneffei

KJ Boyce, L Schreider, L Kirszenblat… - Molecular …, 2011 - Wiley Online Library
In order to cause disease fungal pathogens must be capable of evading or tolerating the
host immune defence system. One commonly utilized evasion mechanism is the ability to …

A dominant mutation in mec-7/β-tubulin affects axon development and regeneration in Caenorhabditis elegans neurons

L Kirszenblat, B Neumann, S Coakley… - Molecular biology of …, 2013 - Am Soc Cell Biol
Microtubules have been known for decades to be basic elements of the cytoskeleton. They
form long, dynamic, rope-like structures within the cell that are essential for mitosis, …

Sleep regulates visual selective attention in Drosophila

L Kirszenblat, D Ertekin, J Goodsell… - Journal of …, 2018 - journals.biologists.com
Although sleep deprivation is known to impair attention in humans and other mammals, the
underlying reasons are not well understood, and whether similar effects are present in non-…

[HTML][HTML] LIN-44/Wnt Directs Dendrite Outgrowth through LIN-17/Frizzled in C. elegans Neurons

L Kirszenblat, D Pattabiraman, MA Hilliard - PLoS biology, 2011 - journals.plos.org
Nervous system function requires proper development of two functional and morphological
domains of neurons, axons and dendrites. Although both these domains are equally …

Neurexin‐1 regulates sleep and synaptic plasticity in Drosophila melanogaster

A Larkin, MY Chen, L Kirszenblat… - European Journal of …, 2015 - Wiley Online Library
Neurexins are cell adhesion molecules that are important for synaptic plasticity and
homeostasis, although links to sleep have not yet been investigated. We examined the effects of …