Besides genome editing, CRISPR-Cas12a has recently been used for DNA detection
applications with attomolar sensitivity but, to our knowledge, it has not been used for the detection …

Direct cloning of biosynthetic gene clusters (BGCs) from microbial genomes facilitates natural
product-based drug discovery. Here, by combining Cas12a and the advanced features of …

Coenzyme Q 10 (CoQ 10 ) is an important component of the respiratory chain in humans
and some bacteria. As a high-value-added nutraceutical antioxidant, CoQ 10 has excellent …

Directly cloning of biosynthetic gene clusters (BGCs) from even unculturable microbial
genomes revolutionized nature products-based drug discovery. However, it is still very …

Large biosynthetic gene cluster (BGC) cloning is important for discovering natural product-based
drugs and remains challenging in high GC content microorganisms (eg, Actinobacteria)…

Abstract: BACKGROUND: Preliminary studies have found that Achyranthes bidentata
alcohol extract can induce the directional chondrocyte differentiation of bone marrow …

Cashew nut kernel oil (CNKO) is an important oil source from tropical crops. The lipid species,
composition, and relative content of CNKO were revealed using ultra high performance …

Graphs have provided an expressive mathematical tool to model quantum-mechanical devices
and systems. In particular, it has been recently discovered that graph theory can be used …

The environment of the urban fringe is complex and frangible. With the acceleration of
industrialization and urbanization, the urban fringe has become the primary space for urban …

RNA molecules perform various crucial roles in diverse cellular processes, from translating
genetic information to decoding the genome, regulating gene expression and catalyzing …