Emerging roles for platelets as immune and inflammatory cells
CN Morrell, AA Aggrey, LM Chapman… - Blood, The Journal of …, 2014 - ashpublications.org
Despite their small size and anucleate status, platelets have diverse roles in vascular biology.
Not only are platelets the cellular mediator of thrombosis, but platelets are also immune …
Not only are platelets the cellular mediator of thrombosis, but platelets are also immune …
Platelets present antigen in the context of MHC class I
LM Chapman, AA Aggrey, DJ Field… - The Journal of …, 2012 - journals.aai.org
Platelets are most recognized for their vital role as the cellular mediator of thrombosis, but
platelets also have important immune functions. Platelets initiate and sustain vascular …
platelets also have important immune functions. Platelets initiate and sustain vascular …
A robust benchmark for germline structural variant detection
New technologies and analysis methods are enabling genomic structural variants (SVs) to
be detected with ever-increasing accuracy, resolution, and comprehensiveness. Translating …
be detected with ever-increasing accuracy, resolution, and comprehensiveness. Translating …
[HTML][HTML] Integration of adeno-associated virus (AAV) into the genomes of most Thai and Mongolian liver cancer patients does not induce oncogenesis
…, LM Chapman, EM Gertz, A Budhu, M Forgues… - BMC genomics, 2021 - Springer
Background Engineered versions of adeno-associated virus (AAV) are commonly used in
gene therapy but evidence revealing a potential oncogenic role of natural AAV in …
gene therapy but evidence revealing a potential oncogenic role of natural AAV in …
miR-451 limits CD4+ T cell proliferative responses to infection in mice
LM Chapman, SK Ture, DJ Field, CN Morrell - Immunologic research, 2017 - Springer
MicroRNAs (miRNAs) are major regulators of cell responses, particularly in stressed cell
states and host immune responses. Some miRNAs have a role in pathogen defense, including …
states and host immune responses. Some miRNAs have a role in pathogen defense, including …
[HTML][HTML] A crowdsourced set of curated structural variants for the human genome
LM Chapman, N Spies, P Pai, CS Lim… - PLoS computational …, 2020 - journals.plos.org
A high quality benchmark for small variants encompassing 88 to 90% of the reference genome
has been developed for seven Genome in a Bottle (GIAB) reference samples. However a …
has been developed for seven Genome in a Bottle (GIAB) reference samples. However a …
SVCurator: a crowdsourcing app to visualize evidence of structural variants for the human genome
A high quality benchmark for small variants encompassing 88 to 90% of the reference genome
has been developed for seven Genome in a Bottle (GIAB) reference samples. However a …
has been developed for seven Genome in a Bottle (GIAB) reference samples. However a …
Collaboration in maternity care: a randomised controlled trial comparing community-based continuity of care with standard hospital care
…, A Sheehan, LM Barclay, J Wills, MG Chapman - British Journal of …, 2001 - Elsevier
Objective To test whether a new community-based model of continuity of care provided by
midwives and obstetricians improved maternal clinical outcomes, in particular a reduced …
midwives and obstetricians improved maternal clinical outcomes, in particular a reduced …
A robust benchmark for detection of germline large deletions and insertions
New technologies and analysis methods are enabling genomic structural variants (SVs) to
be detected with ever-increasing accuracy, resolution and comprehensiveness. To help …
be detected with ever-increasing accuracy, resolution and comprehensiveness. To help …
[PDF][PDF] Translocation of sickle cell erythrocyte microRNAs into Plasmodium falciparum inhibits parasite translation and contributes to malaria resistance
Erythrocytes carrying a variant hemoglobin allele (HbS), which causes sickle cell disease
and resists infection by the malaria parasite Plasmodium falciparum. The molecular basis of …
and resists infection by the malaria parasite Plasmodium falciparum. The molecular basis of …