[HTML][HTML] Efficient assembly and secretion of recombinant subviral particles of the four dengue serotypes using native prM and E proteins

PG Wang, M Kudelko, J Lo, LYL Siu, KTH Kwok… - PLoS …, 2009 - journals.plos.org
Background Flavivirus infected cells produce infectious virions and subviral particles, both
of which are formed by the assembly of prM and E envelope proteins and are believed to …

[HTML][HTML] Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles

MY Li, TS Naik, LYL Siu, O Acuto, E Spooner… - Nature …, 2020 - nature.com
Among the various host cellular processes that are hijacked by flaviviruses, few mechanisms
have been described with regard to viral egress. Here we investigate how flaviviruses …

Activation of Src-family kinases orchestrate secretion of flaviviruses by targeting mature progeny virions to secretory autophagosomes

MY Li, TS Naik, LYL Siu, O Acuto, E Spooner, P Wang… - bioRxiv, 2020 - biorxiv.org
Among the various host cellular processes that are hijacked by flaviviruses, very few
mechanisms have been described with regard to viral secretion. Here we investigated how …

Targeting ARF4-mediated intracellular transport as broad-spectrum antivirals

CF Qin, MY Li, K Deng, XH Cheng, LYL Siu, TS Naik… - 2024 - researchsquare.com
Host factors that regulate cellular vesicular trafficking also contribute to progeny virions’
destination, thus representing as potential antiviral drug targets. Here we demonstrate that …

[PDF][PDF] KDEL receptors assist dengue virus exit from the endoplasmic reticulum

MY Li, M Grandadam, K Kwok, T Lagache, YL Siu… - Cell reports, 2015 - cell.com
Membrane receptors at the surface of target cells are key host factors for virion entry; however,
it is unknown whether trafficking and secretion of progeny virus requires host intracellular …

A community-based study on the association between insomnia and hypothalamic-pituitary-adrenal axis: sex and pubertal influences

J Zhang, SP Lam, SX Li, RCW Ma… - The Journal of …, 2014 - academic.oup.com
Context: The association between insomnia disorder and the hypothalamic-pituitary-adrenal
(HPA) axis needs to be explored in both adults and adolescents. Objectives: Our objective …

Roles of the gut virome and mycobiome in faecal microbiota transplantation

S Lam, X Bai, AN Shkoporov, H Park, X Wu… - The Lancet …, 2022 - thelancet.com
Faecal microbiota transplantation (FMT) is an innovative approach to treat diseases that are
associated with gut dysbiosis, by transferring a healthy stool microbiota to a recipient with …

Synthesis and characterization of luminescent rhenium (I) tricarbonyl diimine complexes with a triarylboron moiety and the study of their fluoride ion-binding properties

ST Lam, N Zhu, VWW Yam - Inorganic chemistry, 2009 - ACS Publications
A series of alkynylrhenium(I) tricarbonyl diimine complexes with a triarylboron moiety has
been synthesized and characterized. The binding properties of the complex toward fluoride …

Anxiety and depression in adolescents with epilepsy

KL Kwong, D Lam, S Tsui, M Ngan… - Journal of child …, 2016 - journals.sagepub.com
The present study examined anxiety and depression in adolescents with epilepsy and the
association of these disorders with seizure-related and sociodemographic variables. The …

Declining trends of cardiovascular-renal complications and mortality in type 2 diabetes: the Hong Kong Diabetes Database

…, NT Cheung, ST Ho, KSL Lam, LWL Yu… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE Nationwide studies on secular trends of diabetes complications are not available
in Asia. We examined changes in risk factor control and incidence of complications from …