The expression of Ki67 is strongly associated with tumor cell proliferation and growth, and is
widely used in routine pathological investigation as a proliferation marker. The nuclear …

You‐Zhi Ma (Corresponding author) Plants have acquired sophisticated stress response
systems to adapt to changing environments. It is important to understand plants’ stress …

Expansins are cell wall proteins that induce pH-dependent wall extension and stress relaxation
in a characteristic and unique manner. Two families of expansins are known, named α- …

The ongoing outbreak of viral pneumonia in China and across the world is associated with
a new coronavirus, SARS-CoV-2 1. This outbreak has been tentatively associated with a …

Viral infection or stimulation of TLR3 triggers signaling cascades, leading to activation of the
transcription factors IRF-3 and NF-κB, which collaborate to induce transcription of type I …

We report observation of holographic surface relief gratings with relatively large amplitude
on a second order nonlinear optical polymeric material. Surface relief gratings on these …

KRAS G12C was recently identified to be potentially druggable by allele-specific covalent
targeting of Cys-12 in vicinity to an inducible allosteric switch II pocket (S-IIP). Success of this …

KRAS gain-of-function mutations occur in approximately 30% of all human cancers. Despite
more than 30 years of KRAS-focused research and development efforts, no targeted therapy …

Mutations in the PTEN induced putative kinase 1 (PINK1) gene cause an autosomal recessive
form of Parkinson disease (PD). So far, no substrates of PINK1 have been reported, and …

Alzheimer's disease (AD) and Parkinson's disease (PD) are the two most common
neurodegenerative diseases that occur either in relatively rare, familial forms or in common, sporadic …