The RNA genomes of picornaviruses are translated into single polyproteins which are
subsequently cleaved into structural and non-structural protein products. For genetic economy, …

Recombination is one of the determinants of genetic diversity in the foot-and-mouth disease
virus (FMDV). FMDV sequences have a mosaic structure caused by extensive intra- and inter…

… Lidia Lasecka-Dykes, Caroline F. Wright and Grace Logan sequenced FMDV isolates; Lidia
Lasecka-Dykes… King acquisitioned the funding; Lidia Lasecka-Dykes wrote the initial draft of …

Nonenveloped viruses protect their genomes by packaging them into an outer shell or capsid
of virus-encoded proteins. Packaging and capsid assembly in RNA viruses can involve …

Viruses can evolve to respond to immune pressures conferred by specific antibodies
generated after vaccination and/or infection. In this study, an in vitro system was developed to …

High-throughput sequencing such as those provided by Illumina are an efficient way to
understand sequence variation within viral populations. However, challenges exist in …

Non-coding regions of viral RNA (vRNA) genomes are critically important in the regulation
of gene expression. In particular, pseudoknot (PK) structures, which are present in a wide …

… Luke, Lidia Lasecka-Dykes, and Sarah Gold carried out experimental work and analyzed
data. … Lidia Lasecka-Dykes and Caroline F. Wright sequenced FMDV isolates and analyzed …

Secondary and tertiary RNA structures play key roles in genome replication of picornaviruses.
Complex, functional structures are particularly abundant in the untranslated regions, …

… Lidia Lasecka-Dykes … King, DJ; Freimanis, G.; Neil, C.; Shaw, A.; Tuthill, TJ; Laing, E.;
King, DP; Lasecka-Dykes, L. Establishing an In Vitro System to Assess How Specific …