User profiles for Lieven Clement
Lieven ClementAssociate Professor in Statistical Genomics, Ghent University Verified email at ugent.be Cited by 4249 |
RNA sequencing data: hitchhiker's guide to expression analysis
Gene expression is the fundamental level at which the results of various genetic and regulatory
programs are observable. The measurement of transcriptome-wide gene expression has …
programs are observable. The measurement of transcriptome-wide gene expression has …
Initial community evenness favours functionality under selective stress
L Wittebolle, M Marzorati, L Clement, A Balloi… - Nature, 2009 - nature.com
Owing to the present global biodiversity crisis, the biodiversity–stability relationship and the
effect of biodiversity on ecosystem functioning have become major topics in ecology 1 , 2 , 3 . …
effect of biodiversity on ecosystem functioning have become major topics in ecology 1 , 2 , 3 . …
Experimental design and data-analysis in label-free quantitative LC/MS proteomics: A tutorial with MSqRob
Label-free shotgun proteomics is routinely used to assess proteomes. However, extracting
relevant information from the massive amounts of generated data remains difficult. This …
relevant information from the massive amounts of generated data remains difficult. This …
[HTML][HTML] Trajectory-based differential expression analysis for single-cell sequencing data
Trajectory inference has radically enhanced single-cell RNA-seq research by enabling the
study of dynamic changes in gene expression. Downstream of trajectory inference, it is vital to …
study of dynamic changes in gene expression. Downstream of trajectory inference, it is vital to …
Leaf responses to mild drought stress in natural variants of Arabidopsis
Although the response of plants exposed to severe drought stress has been studied extensively,
little is known about how plants adapt their growth under mild drought stress conditions. …
little is known about how plants adapt their growth under mild drought stress conditions. …
Identification of novel causative genes determining the complex trait of high ethanol tolerance in yeast using pooled-segregant whole-genome sequence analysis
…, A Goovaerts, K Souvereyns, L Clement… - Genome …, 2012 - genome.cshlp.org
High ethanol tolerance is an exquisite characteristic of the yeast Saccharomyces cerevisiae,
which enables this microorganism to dominate in natural and industrial fermentations. Up to …
which enables this microorganism to dominate in natural and industrial fermentations. Up to …
[HTML][HTML] Observation weights unlock bulk RNA-seq tools for zero inflation and single-cell applications
Dropout events in single-cell RNA sequencing (scRNA-seq) cause many transcripts to go
undetected and induce an excess of zero read counts, leading to power issues in differential …
undetected and induce an excess of zero read counts, leading to power issues in differential …
Measuring the biodiversity of microbial communities by flow cytometry
Measuring the microbial diversity in natural and engineered environments is important for
ecosystem characterization, ecosystem monitoring and hypothesis testing. Although the …
ecosystem characterization, ecosystem monitoring and hypothesis testing. Although the …
Flow cytometry for fast microbial community fingerprinting
Characterizing the microbial community of water is important in different domains, ranging
from food and beverage production to wastewater treatment. Conventional methods, such as …
from food and beverage production to wastewater treatment. Conventional methods, such as …
Probabilistic index models
We present a semiparametric statistical model for the probabilistic index which can be defined
as P(Y⩽Y * ), where Y and Y * are independent random response variables associated …
as P(Y⩽Y * ), where Y and Y * are independent random response variables associated …