User profiles for Likhitha Kolla
 | Likhitha KollaMD/PhD Student, University of Pennsylvania Verified email at pennmedicine.upenn.edu Cited by 369 |
[HTML][HTML] Characterization of the development of the mouse cochlear epithelium at the single cell level
Mammalian hearing requires the development of the organ of Corti, a sensory epithelium
comprising unique cell types. The limited number of each of these cell types, combined with …
comprising unique cell types. The limited number of each of these cell types, combined with …
Performance drift in a mortality prediction algorithm among patients with cancer during the SARS-CoV-2 pandemic
Sudden changes in health care utilization during the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) pandemic may have impacted the performance of clinical …
coronavirus 2 (SARS-CoV-2) pandemic may have impacted the performance of clinical …
The coming of age of nucleic acid vaccines during COVID-19
In the 21st century, several emergent viruses have posed a global threat. Each pathogen has
emphasized the value of rapid and scalable vaccine development programs. The ongoing …
emphasized the value of rapid and scalable vaccine development programs. The ongoing …
Application of traditional vaccine development strategies to SARS-CoV-2
Over the past 150 years, vaccines have revolutionized the relationship between people and
disease. During the COVID-19 pandemic, technologies such as mRNA vaccines have …
disease. During the COVID-19 pandemic, technologies such as mRNA vaccines have …
The case for AI-driven cancer clinical trials–The efficacy arm in silico
Pharmaceutical agents in oncology currently have high attrition rates from early to late
phase clinical trials. Recent advances in computational methods, notably causal artificial …
phase clinical trials. Recent advances in computational methods, notably causal artificial …
Science over stigma: the need for evidence-based blood donation policies for men who have sex with men in the USA
The ongoing COVID-19 pandemic has decimated the US blood product supply, with more
than 46 000 community-based blood drives cancelled as of September, 2020, resulting in the …
than 46 000 community-based blood drives cancelled as of September, 2020, resulting in the …
Uses and limitations of artificial intelligence for oncology
L Kolla, RB Parikh - Cancer, 2024 - Wiley Online Library
Modern artificial intelligence (AI) tools built on high‐dimensional patient data are reshaping
oncology care, helping to improve goal‐concordant care, decrease cancer mortality rates, …
oncology care, helping to improve goal‐concordant care, decrease cancer mortality rates, …
[HTML][HTML] SARS-CoV-2 and COVID-19: An evolving review of diagnostics and therapeutics
…, DN Rafizadeh, AN Skelly, MB Guebila, L Kolla… - 2021 - greenelab.github.io
Since late 2019, Coronavirus disease 2019 (COVID-19) has spread around the world,
resulting in the declaration of a pandemic by the World Health Organization (WHO). This …
resulting in the declaration of a pandemic by the World Health Organization (WHO). This …
[HTML][HTML] SUMO targeting of a stress-tolerant Ulp1 SUMO protease
SUMO proteases of the SENP/Ulp family are master regulators of both sumoylation and
desumoylation and regulate SUMO homeostasis in eukaryotic cells. SUMO conjugates rapidly …
desumoylation and regulate SUMO homeostasis in eukaryotic cells. SUMO conjugates rapidly …
[HTML][HTML] High content screen for identifying small-molecule LC3B-localization modulators in a renal cancer cell line
L Kolla, DS Heo, DP Rosenberg, SA Barlow… - Scientific data, 2018 - nature.com
Forms of selective autophagy have now been recognized to regulate flux in many intracellular
processes. Specific pathways and functions have been identified for mitophagy, ERphagy, …
processes. Specific pathways and functions have been identified for mitophagy, ERphagy, …