We have investigated the genetic and epigenetic changes of a newly isolated tumor suppressor
gene on 3p21.3, RASSF1A, in nasopharyngeal carcinoma (NPC). Four xenografts, four …

Deletion on the short arm of chromosome 3 is one of the most important genetic abnormalities
in the tumorigenesis of nasopharyngeal carcinoma (NPC). Both physical mapping and …

Gossypol, a male contraceptive drug extracted from cottonseeds, has been found to have
antiproliferative activity on tumour cells and is thought to be a potential anticancer drug. The …

Deletion of 11q23 is a common genetic aberration in nasopharyngeal carcinoma (NPC).
Multiple candidate tumor suppressor genes (TSG) were mapped to this region but few of them …

Deletion of the short arm of chromosome 3 is a common event in nasopharyngeal carcinoma
(NPC), suggesting that one or more tumor suppressor genes at 3p are involved in this …

Chronic rhinosinusitis (CRS) is a common condition associated with inflammation and tissue
remodeling of the nose and paranasal sinuses, frequently occurring with nasal polyps and …

Tazarotene‐induced gene 1 (TIG1) and Tazarotene‐induced gene 3 (TIG3) are retinoid acid
(RA) target genes as well as candidate tumor suppressor genes in human cancers. In our …

Aberrant retinoid signaling in human cancers is extending from the nucleus to the cytoplasm.
Recently, we have demonstrated frequent epigenetic inactivation of a retinoic acid receptor …

Ras-association domain family of proteins (RASSF) is characterized by the Ras-association
(RA) domain at the C-terminal. Frequent inactivation of RASSF1A gene in human cancers …

Background and Objectives: This study aimed to identify demographic and clinical factors at
the time of critical care consultation associated with mortality or intensive care unit …