User profiles for Lina M. Leon
 | Lina LeonCRISPR-Cas genome engineer, Scientist Verified email at ucsf.edu Cited by 607 |
Discovery of widespread type I and type V CRISPR-Cas inhibitors
Bacterial CRISPR-Cas systems protect their host from bacteriophages and other mobile genetic
elements. Mobile elements, in turn, encode various anti-CRISPR (Acr) proteins to inhibit …
elements. Mobile elements, in turn, encode various anti-CRISPR (Acr) proteins to inhibit …
A compact Cascade–Cas3 system for targeted genome engineering
CRISPR–Cas technologies have enabled programmable gene editing in eukaryotes and
prokaryotes. However, the leading Cas9 and Cas12a enzymes are limited in their ability to …
prokaryotes. However, the leading Cas9 and Cas12a enzymes are limited in their ability to …
A bacteriophage nucleus-like compartment shields DNA from CRISPR nucleases
All viruses require strategies to inhibit or evade the immune pathways of cells that they infect.
The viruses that infect bacteria, bacteriophages (phages), must avoid immune pathways …
The viruses that infect bacteria, bacteriophages (phages), must avoid immune pathways …
Mobile element warfare via CRISPR and anti-CRISPR in Pseudomonas aeruginosa
Bacteria deploy multiple defenses to prevent mobile genetic element (MGEs) invasion.
CRISPR–Cas immune systems use RNA-guided nucleases to target MGEs, which counter with …
CRISPR–Cas immune systems use RNA-guided nucleases to target MGEs, which counter with …
How bacteria control the CRISPR-Cas arsenal
… Author links open overlay panel Lina M Leon 1 , Senén D Mendoza 1 , Joseph Bondy-…
into methyltransferases (MT, S 1 M 2 ) and restriction-competent holoenzymes (S 1 M 2 R 2 ). …
into methyltransferases (MT, S 1 M 2 ) and restriction-competent holoenzymes (S 1 M 2 R 2 ). …
[HTML][HTML] Impacto en la salud y el medio ambiente por exposición a plaguicidas e implementación de buenas prácticas agrícolas en el cultivo de tomate, Colombia …
…, N Carvajal, E Barbosa, LM León… - Rev. chil. salud …, 2012 - pesquisa.bvsalud.org
Objetivo: describir los posibles efectos adversos en salud y medio ambiente por el uso de
plaguicidas en zonas productoras de Colombia e implementar las buenas prácticas agrícolas …
plaguicidas en zonas productoras de Colombia e implementar las buenas prácticas agrícolas …
A nucleus-like compartment shields bacteriophage DNA from CRISPR-Cas and restriction nucleases
All viruses require strategies to inhibit or evade the immunity pathways of cells they infect.
The viruses that infect bacteria, bacteriophages (phages), must avoid nucleic-acid targeting …
The viruses that infect bacteria, bacteriophages (phages), must avoid nucleic-acid targeting …
Building an action plan to tackle palliative care inequality through multi-stakeholder platforms
…, MX León-Delgado… - Palliative Care and …, 2023 - journals.sagepub.com
Background: To achieve universal care and overcome existing barriers, the most effective
strategy is to devise an action plan that incorporates palliative care into primary health care (…
strategy is to devise an action plan that incorporates palliative care into primary health care (…
[BOOK][B] CRISPR-Cas3: Studying the molecular interactions that drive adaptation & engineering novel bacterial editing tools
LM Leon - 2021 - search.proquest.com
Bacteria deploy multiple defenses to prevent mobile genetic element (MGEs) invasion.
CRISPR-Cas immune systems feature RNA-guided nucleases that target MGEs, which counter …
CRISPR-Cas immune systems feature RNA-guided nucleases that target MGEs, which counter …
A minimal CRISPR-Cas3 system for genome engineering
CRISPR-Cas technologies have provided programmable gene editing tools that have
revolutionized research. The leading CRISPR-Cas9 and Cas12a enzymes are ideal for …
revolutionized research. The leading CRISPR-Cas9 and Cas12a enzymes are ideal for …