[HTML][HTML] Epigenetic activation of WNT5A drives glioblastoma stem cell differentiation and invasive growth
…, LJ Corley, H Yan, J Zhang, Y You, N Liu, L Cai… - Cell, 2016 - cell.com
Glioblastoma stem cells (GSCs) are implicated in tumor neovascularization, invasiveness,
and therapeutic resistance. To illuminate mechanisms governing these hallmark features, we …
and therapeutic resistance. To illuminate mechanisms governing these hallmark features, we …
Adjuvant temozolomide chemotherapy with or without interferon Alfa among patients with newly diagnosed high-grade gliomas: a randomized clinical trial
C Guo, Q Yang, P Xu, M Deng, T Jiang, L Cai… - JAMA Network …, 2023 - jamanetwork.com
Importance High-grade gliomas (HGGs) constitute the most common and aggressive primary
brain tumor, with 5-year survival rates of 30.9% for grade 3 gliomas and 6.6% for grade 4 …
brain tumor, with 5-year survival rates of 30.9% for grade 3 gliomas and 6.6% for grade 4 …
[HTML][HTML] Sensitive detection of EGFR mutations in cerebrospinal fluid from lung adenocarcinoma patients with brain metastases
H Yang, L Cai, Y Zhang, H Tan, Q Deng, M Zhao… - The Journal of Molecular …, 2014 - Elsevier
Epidermal growth factor receptor (EGFR) mutations in cerebrospinal fluid (CSF) might be
useful predictive markers for EGFR tyrosine kinase inhibitor treatment of intracranial metastatic …
useful predictive markers for EGFR tyrosine kinase inhibitor treatment of intracranial metastatic …
[HTML][HTML] International consensus on severe lung cancer—the first edition
…, S Li, J Liu, Q Chu, L Miao, L Cai, X Cai… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Lung cancer is one of the most prevalent and lethal cancers worldwide (1). The traditional
treatments include surgery, chemotherapy, radiotherapy and interventional therapy. The …
treatments include surgery, chemotherapy, radiotherapy and interventional therapy. The …
[HTML][HTML] Whole brain radiotherapy (WBRT) for leptomeningeal metastasis from NSCLC in the era of targeted therapy: a retrospective study
…, W Wang, S Xu, D Liu, M Lu, D Zhu, L Chen, L Cai… - Radiation …, 2020 - Springer
Background and purpose Leptomeningeal metastasis (LM) is a rare but detrimental
complication in patients with non-small cell lung cancer (NSCLC). Although whole brain …
complication in patients with non-small cell lung cancer (NSCLC). Although whole brain …
[HTML][HTML] Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors
J Li, W Jiang, J Wei, J Zhang, L Cai, M Luo… - Journal of Translational …, 2020 - Springer
Background Circulating tumor DNA (ctDNA) offers a convenient way to monitor tumor
progression and treatment response. Because tumor mutational profiles are highly variable from …
progression and treatment response. Because tumor mutational profiles are highly variable from …
[HTML][HTML] Atypical primary central nervous system lymphoma and glioblastoma: multiparametric differentiation based on non-enhancing volume, apparent diffusion …
…, M Lai, C Shi, L Li, K Ye, J Xu, R Ai, C Shan, L Cai… - European …, 2023 - Springer
Objectives To evaluate the multiparametric diagnostic performance with non-enhancing
tumor volume, apparent diffusion coefficient (ADC), and arterial spin labeling (ASL) to …
tumor volume, apparent diffusion coefficient (ADC), and arterial spin labeling (ASL) to …
[HTML][HTML] Bevacizumab as a treatment for radiation necrosis following stereotactic radiosurgery for brain metastases: clinical and radiation dosimetric impacts
J Li, J He, L Cai, M Lai, Q Hu, C Ren… - Annals of Palliative …, 2021 - apm.amegroups.org
Background: Brain necrosis (RN) is a common radiotherapy sequela for brain metastases.
Bevacizumab is identified as a therapeutic strategy for RN. This study aimed to study the …
Bevacizumab is identified as a therapeutic strategy for RN. This study aimed to study the …
Machine learning algorithms utilizing blood parameters enable early detection of immunethrombotic dysregulation in COVID‐19
…, S Wang, J Li, H Yin, M Zhang, L Cai… - Clinical and …, 2021 - Wiley Online Library
Dear Editor, The pandemic of coronavirus disease 2019 (COVID-19) has stressed and
overloaded the existing medical capacity worldwide. From a more pragmatic perspective, the …
overloaded the existing medical capacity worldwide. From a more pragmatic perspective, the …
[PDF][PDF] Cerebrospinal fluid-derived circulating tumor DNA is more comprehensive than plasma in NSCLC patients with leptomeningeal metastases regardless of …
H Yang, L Wen, C Zhao, J Chen, Z Zhou, C Zhou, L Cai… - Heliyon, 2022 - cell.com
Introduction Metastases to the central nervous system (CNS) are devastating neurological
complications. Circulating cell-free tumor DNA (ctDNA) from cerebrospinal fluid (CSF) better …
complications. Circulating cell-free tumor DNA (ctDNA) from cerebrospinal fluid (CSF) better …