Zoonotic pandemics, such as that caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), can follow the spillover of animal viruses into highly susceptible human …

Mumps is caused by the mumps virus ( MuV ), a member of the Paramyxoviridae family of
enveloped, non‐segmented, negative‐sense RNA viruses. Mumps is characterized by painful …

Measles virus (MV) is highly infectious, and has long been thought to enter the host by infecting
epithelial cells of the respiratory tract. However, epithelial cells do not express signaling …

Memory B cell reserves can generate protective antibodies against repeated SARS-CoV-2
infections, but with unknown reach from original infection to antigenically drifted variants. We …

A chimeric antigen receptor-modified T-cell therapy recipient developed severe coronavirus
disease 2019, intractable RNAemia, and viral replication lasting >2 months. Premortem …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), emerged at the end of 2019 and by mid-June 2020 the …

The cytosolic sensor MDA5 is crucial for antiviral innate immune defense against various
RNA viruses including measles virus; as such, many viruses have evolved strategies to …

Globally, there is an urgency to develop effective, low-cost therapeutic interventions for
coronavirus disease 2019 (COVID-19). We previously generated the stable and ultrapotent …

The global increase in measles vaccination has resulted in a significant reduction of measles
mortality. The standard route of administration for the live-attenuated measles virus (MV) …

Effective inactivation of biosafety level 4 (BSL-4) pathogens is vital in order to study these
agents safely. Gamma irradiation is a commonly used method for the inactivation of BSL-4 …