The distribution of 20 variable regions resulting from insertion-deletion events in the
genomes of the tubercle bacilli has been evaluated in a total of 100 strains of Mycobacterium …

The murine homeo box gene Nkx2-5 is expressed in precardiac mesoderm and in the
myocardium of embryonic and fetal hearts. Targeted interruption of Nkx2-5 resulted in abnormal …

We have isolated two murine homeobox genes, Nkx-2.5 and Nkx-2.6, that are new members
of a sp sub-family of homeobox genes related to Drosophila NK2, NK3 and NK4/msh-2. In …

For stakeholders, such as investors and lenders, to appropriately assess a company’s financial
performance, the reported accounting earnings must closely reflect the economic reality …

With an estimated 9.4 million new cases globally, tuberculosis (TB) continues to be a major
public health concern. Eighty percent of all cases worldwide occur in 22 high-burden, mainly …

Multidrug-resistant (MDR) strains of Mycobacterium tuberculosis have emerged worldwide.
In many countries and regions, these resistant strains constitute a serious threat to the …

Rifampin is a cornerstone of modern antituberculosis therapy. However, rifampin's half-life
of 3 h is believed to limit its utility for intermittent therapy, so new congeners with long half-…

Background. Moxifloxacin is a quinolone antimicrobial that has potent activity against
Mycobacterium tuberculosis. To optimize moxifloxacin dose and dose regimen, pharmacodynamic …

Background The Drosophila neoplastic tumor suppressor Lethal (2) giant larvae (Lgl) controls
apicobasal cell polarity and proliferation. We have previously shown that lgl − clones in …

Although the virulences and host ranges differ among members of the Mycobacterium
tuberculosis complex (TBC; M. tuberculosis, M. africanum, M. canettii, M. microti, M. bovis, and M. …