[PDF][PDF] A Plasmodium falciparum histone deacetylase regulates antigenic variation and gametocyte conversion

…, KM Skillman, RHY Jiang, LM Childs, LM Altenhofen… - Cell host & …, 2014 - cell.com
The asexual forms of the malaria parasite Plasmodium falciparum are adapted for chronic
persistence in human red blood cells, continuously evading host immunity using …

Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state

SE Babbitt, L Altenhofen, SA Cobbold… - Proceedings of the …, 2012 - National Acad Sciences
The human malaria parasite Plasmodium falciparum is auxotrophic for most amino acids. Its
amino acid needs are met largely through the degradation of host erythrocyte hemoglobin; …

[HTML][HTML] Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate

…, D Scanfeld, SJ Regenbogen, L Altenhofen… - Cell, 2014 - cell.com
A central problem in biology is to identify gene function. One approach is to infer function in
large supergenomic networks of interactions and ancestral relationships among genes; …

[HTML][HTML] Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite's food vacuole and alter drug sensitivities

…, CM Moore, DA Daley, MJ Hoke, LM Altenhofen… - Scientific reports, 2015 - nature.com
Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are the
major determinant of chloroquine resistance in this lethal human malaria parasite. Here, we …

Epigenetic switches in clag3 genes mediate blasticidin S resistance in malaria parasites

…, VM Crowley, LM Altenhofen… - Cellular …, 2013 - Wiley Online Library
Malaria parasites induce changes in the permeability of the infected erythrocyte membrane
to numerous solutes, including toxic compounds. In P lasmodium falciparum, this is mainly …

Whole-Genome Analysis of Plasmodium spp. Utilizing a New Agilent Technologies DNA Microarray Platform

HJ Painter, LM Altenhofen, BFC Kafsack… - Malaria: Methods and …, 2013 - Springer
The application of DNA microarray technologies to malaria genomics has been widely used
but has been limited by sample availability and technical variability. To address these issues…

PfSR1 controls alternative splicing and steady‐state RNA levels in Plasmodium falciparum through preferential recognition of specific RNA motifs

S Eshar, L Altenhofen, A Rabner, P Ross… - Molecular …, 2015 - Wiley Online Library
P lasmodium species have evolved complex biology to adapt to different hosts and changing
environments throughout their life cycle. Remarkably, these adaptations are achieved by a …

[BOOK][B] The effects of light, temperature, after-ripening, nitrate and water on Chenopodium album seed germination

LM Altenhofen - 2009 - search.proquest.com
Chenopodium album is a widespread and troublesome weed in Iowa and agricultural areas
throughout the north temperate regions of the world. This study investigated the effects of …

[PDF][PDF] Complex regulation of Chenopodium album seed germination

LM Altenhofen, J Dekker - Appl. Ecol. Environ. Sci, 2013 - Citeseer
Chenopodium album is a common, widespread and troublesome weed in agricultural areas
throughout the north temperate regions of the world. A primary reason for this flexible …

Protein domain prediction using context statistics, the false discovery rate, and comparative genomics, with application to Plasmodium falciparum

A Ochoa - 2013 - search.proquest.com
Protein domain prediction is a key step in characterizing protein structure, function, and
evolution. However, the genome of Plasmodium falciparum, the causative agent of malignant …