Emergence of SARS-CoV-2 causing COVID-19 has resulted in hundreds of thousands of
deaths. In search for key targets of effective therapeutics, robust animal models mimicking …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread around the
globe after its emergence in Wuhan in December 2019. With no specific therapeutic and …

The expanding pandemic of coronavirus disease 2019 (COVID-19) requires the development
of safe, efficacious and fast-acting vaccines. Several vaccine platforms are being …

Current COVID-19 vaccines are based on prototypic spike sequences from ancestral 2019
SARS-CoV-2 strains. However, the ongoing pandemic is fueled by variants of concern (VOC) …

SARS-CoV-2 rapidly spread around the globe after its emergence in Wuhan in December
2019. With no specific therapeutic and prophylactic options available, the virus was able to …

Human noroviruses (HuNoVs) are the most common cause of viral gastroenteritis resulting
annually in ~219,000 deaths and a societal cost of ~USD 60 billion, and no antivirals or …

The explosively expanding COVID-19 pandemic urges the development of safe, efficacious
and fast-acting vaccines to quench the unrestrained spread of SARS-CoV-2. Several …

… We thank Carolien de Keyzer, Lindsey Bervoets, Thibault Francken, Niels Cremers,
Jasper Rymenants and Stijn Hendricks for excellent technical assistance with animal …

… Kaptein, Carolien De Keyzer, Lindsey Bervoets, Sarah Debaveye, Madina Rasulova, Laura
Seldeslachts, Li-Hsin Li, Sander Jansen, Michael Bright Yakass, Babs E. Verstrepen, Kinga P…

The emergence of SARS-CoV-2 variants of concern (VoCs) has exacerbated the COVID-19
pandemic. Currently available monoclonal antibodies and vaccines appear to have reduced …