User profiles for Lining Arnold Ju

Lining (Arnold) Ju

Associate Professor | Snow Fellow | PhD Georgia Tech/Emory, BSc PKU
Verified email at sydney.edu.au
Cited by 2121

Computational Modeling for Intelligent Surface Plasmon Resonance Sensor Design and Experimental Schemes for Real‐Time Plasmonic Biosensing: A Review

…, S Neermunda, KV Kong, HP Ho, LA Ju… - Advanced Theory …, 2023 - Wiley Online Library
The spectacular physical phenomenon of surface plasmon resonance (SPR) is the essence
of present‐day plasmonic sensors. Meanwhile, the unique properties of the interaction …

Dynamic bonds and their roles in mechanosensing

C Zhu, Y Chen, LA Ju - Current opinion in chemical biology, 2019 - Elsevier
Mechanical forces are ubiquitous in a cell’s internal structure and external environment.
Mechanosensing is the process that the cell employs to sense its mechanical environment. In …

[HTML][HTML] Micropipette-based biomechanical nanotools on living cells

H Wang, F Zhou, Y Guo, LA Ju - European Biophysics Journal, 2022 - Springer
Mechanobiology is an emerging field at the interface of biology and mechanics, investigating
the roles of mechanical forces within biomolecules, organelles, cells, and tissues. As a …

An integrin αIIbβ3 intermediate affinity state mediates biomechanical platelet aggregation

Y Chen, LA Ju, F Zhou, J Liao, L Xue, QP Su, D Jin… - Nature materials, 2019 - nature.com
Integrins are membrane receptors that mediate cell adhesion and mechanosensing. The
structure–function relationship of integrins remains incompletely understood, despite the …

Enabling peristalsis of human colon tumor organoids on microfluidic chips

…, R Al-Nakashli, R Chapman, Y Zhang, LA Ju… - …, 2021 - iopscience.iop.org
Peristalsis in the digestive tract is crucial to maintain physiological functions. It remains
challenging to mimic the peristaltic microenvironment in gastrointestinal organoid culture. Here, …

[HTML][HTML] Hemodynamic analysis for stenosis microfluidic model of thrombosis with refined computational fluid dynamics simulation

…, T Goh, R Michelis, K Kyanian, Y Zhang, Z Li, LA Ju - Scientific reports, 2021 - nature.com
Disturbed blood flow has been increasingly recognized for its critical role in platelet aggregation
and thrombosis. Microfluidics with hump shaped contractions have been developed to …

Upconversion nonlinear structured illumination microscopy

…, X Di, J Liao, S Wen, QP Su, X Shan, ZQ Xu, LA Ju… - Nano …, 2020 - ACS Publications
Video-rate super-resolution imaging through biological tissue can visualize and track
biomolecule interplays and transportations inside cellular organisms. Structured illumination …

Novel Movable Typing for Personalized Vein‐Chips in Large Scale: Recapitulate Patient‐Specific Virchow's Triad and its Contribution to Cerebral Venous Sinus …

…, Y Wang, F Passam, T Ang, LA Ju - Advanced Functional …, 2023 - Wiley Online Library
The Vein‐Chip recapitulates CVST Virchow's triad and enables systematic characterization
of venous thrombogenesis with respect to fibrin formation and platelet aggregation. Distinct …

[HTML][HTML] Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations

…, M Yao, Y Guo, ZY Yu, Y Ramaswamy, LA Ju… - Communications …, 2021 - nature.com
Mechanosensitive channels are integral membrane proteins that sense mechanical stimuli.
Like most plasma membrane ion channel proteins they must pass through biosynthetic …

Ultra-stable biomembrane force probe for accurately determining slow dissociation kinetics of PD-1 blockade antibodies on single living cells

…, BF Ju, P Obeidy, YC Zhao, X Tu, W Fang, LA Ju… - Nano Letters, 2020 - ACS Publications
Immune checkpoint blockade with monoclonal antibodies (mAbs) that target programmed
cell death protein-1 (PD-1) has remarkably revolutionized cancer therapy. Their binding …