Tauvid has been approved by the US Food and Drug Administration (FDA) in 2020 for
positron emission tomography (PET) imaging of adult patients with cognitive impairments …

The endocannabinoid system (ECS) is involved in a wide range of biological functions and
comprises cannabinoid receptors and enzymes responsible for endocannabinoid synthesis …

Positron emission tomography (PET) is an important diagnostic tool in modern medicine
due to its ability to locate and assess abnormalities in neurology,[1a–e] oncology,[1f–j] and …

Large neutral l-amino acids are substrates of system L amino acid transporters. The level of
one of these, LAT1, is increased in many tumors. Aromatic l-amino acids may also be …

In the search for an efficient, fluorine-18 labeled amino acid based radiotracer for tumor
imaging with positron emission tomography (PET), two new tryptophan analogs were …

Cannabinoid receptor CB 2 (CB 2 R) is upregulated on activated microglia and astrocytes in
the brain under inflammatory conditions and plays important roles in many neurological …

The gastrin-releasing peptide receptor (GRPr) is overexpressed on various human tumors.
The goal of our study was the synthesis of new 18 F-labeled bombesin analogues for the PET …

Methods for the radiolabeling molecules of interest with [ 18 F]-fluoride need to be rapid,
convenient, and efficient. Numerous [ 18 F]-labeled prosthetic groups, eg, N-succinimidyl 4 [ 18 F…

A new method for the 18 F‐radiolabeling of aromatic compounds based on the aromatic
nucleophilic substitution (S N Ar) reaction using triarylsulfonium salts has been developed. …

Free energy changes of each elementary step involved in the formal hydride transfer (H - T )
reactions (including the so-called “one-step” H - T and “multistep” H - T mechanisms) of the …