User profiles for Lionel Porcar

Lionel PORCAR

Institut Laue Langevin
Verified email at ill.fr
Cited by 7675

Formation of the dynamic clusters in concentrated lysozyme protein solutions

L Porcar, P Falus, WR Chen, A Faraone… - The Journal of …, 2010 - ACS Publications
Neutron spin echo (NSE) and small angle neutron scattering (SANS) were used to investigate
the correlation between structure and short-time dynamics of lysozyme solutions in the …

Lysozyme protein solution with an intermediate range order structure

Y Liu, L Porcar, J Chen, WR Chen, P Falus… - The Journal of …, 2011 - ACS Publications
The formation of equilibrium clusters has been studied in both a prototypical colloidal system
and protein solutions. The appearance of a low-Q correlation peak in small angle scattering …

Flow-SANS and Rheo-SANS applied to soft matter

APR Eberle, L Porcar - Current opinion in colloid & interface science, 2012 - Elsevier
We review the current literature pertaining to the characterization of soft matter subject to flow
utilizing small-angle neutron scattering, flow-SANS, with an emphasis on the simultaneous …

Spatially resolved small-angle neutron scattering in the 1-2 plane: A study of shear-induced phase-separating wormlike micelles

MW Liberatore, F Nettesheim, NJ Wagner, L Porcar - Physical Review E, 2006 - APS
The shear-induced microstructure of a shear-induced phase separating (SIPS) wormlike
micellar solution is measured by combining small-angle neutron scattering with a shear cell …

Lipid bilayers and membrane dynamics: insight into thickness fluctuations

AC Woodka, PD Butler, L Porcar, B Farago, M Nagao - Physical review letters, 2012 - APS
Thickness fluctuations have long been predicted in biological membranes but never directly
observed experimentally. Here, we utilize neutron spin echo spectroscopy to experimentally …

Apolipoprotein E binding drives structural and compositional rearrangement of mRNA-containing lipid nanoparticles

F Sebastiani, M Yanez Arteta, M Lerche, L Porcar… - ACS …, 2021 - ACS Publications
Emerging therapeutic treatments based on the production of proteins by delivering mRNA
have become increasingly important in recent times. While lipid nanoparticles (LNPs) are …

[PDF][PDF] Noninvasive neutron scattering measurements reveal slower cholesterol transport in model lipid membranes

S Garg, L Porcar, AC Woodka, PD Butler… - Biophysical journal, 2011 - cell.com
Proper cholesterol transport is essential to healthy cellular activity and any abnormality can
lead to several fatal diseases. However, complete understandings of cholesterol …

Microstructure and shear rheology of entangled wormlike micelles in solution

…, NJ Wagner, EW Kaler, LP Cook, L Porcar… - Journal of …, 2009 - pubs.aip.org
The shear rheology of a model wormlike micellar solution exhibits moderate shear thinning
and curved flow velocity profiles without discontinuity (nonbanding case). The shear …

[HTML][HTML] SEC-SANS: size exclusion chromatography combined in situ with small-angle neutron scattering

…, C Merrick, J Devos, VT Forsyth, L Porcar… - Journal of applied …, 2016 - scripts.iucr.org
The first implementation and use of an in situ size exclusion chromatography (SEC) system
on a small-angle neutron scattering instrument (SANS) is described. The possibility of …

[PDF][PDF] Observation of small cluster formation in concentrated monoclonal antibody solutions and its implications to solution viscosity

…, T Perevozchikova, H Zhang, P Falus, L Porcar… - Biophysical journal, 2014 - cell.com
Monoclonal antibodies (mAbs) are a major class of biopharmaceuticals. It is hypothesized
that some concentrated mAb solutions exhibit formation of a solution phase consisting of …