[PDF][PDF] Molecular evolution of early-onset prostate cancer identifies molecular risk markers and clinical trajectories

…, N Saini, AM Stütz, D Weichenhan, LM Böttcher… - Cancer cell, 2018 - cell.com
Identifying the earliest somatic changes in prostate cancer can give important insights into
tumor evolution and aids in stratifying high- from low-risk disease. We integrated whole …

[HTML][HTML] Determination of PD-L1 expression in circulating tumor cells of NSCLC patients and correlation with response to PD-1/PD-L1 inhibitors

…, S Schatz, M Falk, LA Berger, LM Böttcher… - Cancers, 2019 - mdpi.com
Circulating tumor cells (CTCs) hold great potential to answer key questions of how non-small
cell lung cancer (NSCLC) evolves and develops resistance upon anti-PD-1/PD-L1 …

[PDF][PDF] Platelets fuel the inflammasome activation of innate immune cells

V Rolfes, LS Ribeiro, I Hawwari, L Böttcher, N Rosero… - Cell reports, 2020 - cell.com
The inflammasomes control the bioactivity of pro-inflammatory cytokines of the interleukin (IL)-1
family. The inflammasome assembled by NLRP3 has been predominantly studied in …

The alarmin S100A9 hampers osteoclast differentiation from human circulating precursors by reducing the expression of RANK

…, JHA Martens, E Habibi, LM Böttcher… - The FASEB …, 2019 - Wiley Online Library
The alarmin S100A8/A9 is implicated in sterile inflammation‐induced bone resorption and
has been shown to increase the bone‐resorptive capacity of mature osteoclasts. Here, we …

The Virtual Child

RJ Gilbertson, S Behjati, AL Böttcher, ME Bronner… - Cancer Discovery, 2024 - AACR
We are building the world's first Virtual Child–a computer model of normal and cancerous
human development at the level of each individual cell. The Virtual Child will “develop cancer” …

Zur Förderung der Allgemeinheit nach § 52 Abs. 1 Satz 1, 2 AO durch gemeinnützige Bildungseinrichtungen

L Böttcher, S Kaelberlah - RdJB Recht der Jugend und des …, 2024 - nomos-elibrary.de
Anlässlich zweier neuerer BFH-Entscheidungen betreffend die Frage nach der Förderung
der Allgemeinheit behandelt der folgende Beitrag die Voraussetzungen, die an dieses …

Salvia josetta (Nepetoideae; Lamiaceae), a new species from Lebanon

H EL ZEIN, L BOTTCHER - Phytotaxa, 2024 - phytotaxa.mapress.com
Salvia josetta, a new species of Lamiaceae, is described and illustrated. The species was
discovered in 2018 from the district of Danniye, North Lebanon. We collected samples each …

[PDF][PDF] Georg Wydra

T Bauer, J Bissen, L Böttcher, N Christian, S Debra… - sportpaedagogik-sb.de
Von den Beobachtern wurden die verschiedenen Stundeninhalte und deren zeitliche Dauer
erfasst. In der Mehrzahl der Sportstunden wurden mehrere Inhalte realisiert. In 79 …

INSP-15. ITCC-P4: A sustainable platform of molecularly well-characterized PDX models of pediatric cancers for high throughputin vivo testing

…, N Mack, B Schwalm, AL Böttcher… - Neuro …, 2022 - academic.oup.com
Convection enhanced delivery (CED), an alternative to systemic chemotherapy, spans
nearly two decades of clinical experience. The application of CED in pediatric neuro-oncology …

ITCC-P4: Genomic profiling and analyses of pediatric patient tumor and patient-derived xenograft (PDX) models for high throughput in vivo testing

…, C Previti, L Weiser, I Buchhalter, AL Böttcher… - Cancer Research, 2023 - AACR
Advancements in state-of-the-art molecular profiling techniques have resulted in better
understanding of pediatric cancers and driver events. It has become apparent that pediatric …