User profiles for Lisa Goers
Lisa GoersHarvard Medical School, MGH Verified email at mgh.harvard.edu Cited by 1179 |
Co-culture systems and technologies: taking synthetic biology to the next level
Co-culture techniques find myriad applications in biology for studying natural or synthetic
interactions between cell populations. Such techniques are of great importance in synthetic …
interactions between cell populations. Such techniques are of great importance in synthetic …
Emerging strategies for engineering Escherichia coli Nissle 1917-based therapeutics
Engineered microbes are rapidly being developed for the delivery of therapeutic modalities
to sites of disease. Escherichia coli Nissle 1917 (EcN), a genetically tractable probiotic with a …
to sites of disease. Escherichia coli Nissle 1917 (EcN), a genetically tractable probiotic with a …
Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes
INTRODUCTION Detection of pathogens by the innate immune system is an essential first
step in successful host defense against infection. Pathogens are typically detected by germline…
step in successful host defense against infection. Pathogens are typically detected by germline…
NAIP–NLRC4-deficient mice are susceptible to shigellosis
PS Mitchell, JL Roncaioli, EA Turcotte, L Goers… - Elife, 2020 - elifesciences.org
Bacteria of the genus Shigella cause shigellosis, a severe gastrointestinal disease that is a
major cause of diarrhea-associated mortality in humans. Mice are highly resistant to Shigella …
major cause of diarrhea-associated mortality in humans. Mice are highly resistant to Shigella …
Shigella IpaH9.8 limits GBP1-dependent LPS release from intracytosolic bacteria to suppress caspase-4 activation
L Goers, K Kim, TC Stedman… - Proceedings of the …, 2023 - National Acad Sciences
Pyroptosis is an inflammatory form of cell death induced upon recognition of invading microbes.
During an infection, pyroptosis is enhanced in interferon-gamma-exposed cells via the …
During an infection, pyroptosis is enhanced in interferon-gamma-exposed cells via the …
Whole‐cell Escherichia coli lactate biosensor for monitoring mammalian cell cultures during biopharmaceutical production
Many high‐value added recombinant proteins, such as therapeutic glycoproteins, are produced
using mammalian cell cultures. In order to optimize the productivity of these cultures it is …
using mammalian cell cultures. In order to optimize the productivity of these cultures it is …
Engineering microbial biosensors
The use of biological entities as ‘sensors’ has long been of interest to engineers and
biologists. With recent advances in our ability to engineer biology, potential biosensors can be …
biologists. With recent advances in our ability to engineer biology, potential biosensors can be …
[BOOK][B] Novel in vivo biosensors for monitoring of mammalian cell cultures
L Goers - 2015 - core.ac.uk
Mammalian cell cultures are used for production of biopharmaceuticals, eg monoclonal
antibodies. Only mammalian hybridoma cells contain the pathways for antibody production, but …
antibodies. Only mammalian hybridoma cells contain the pathways for antibody production, but …
Cover Image, Volume 114, Number 6, June 2017
… Lisa Goers, Catherine Ainsworth, Cher Hui Goey, Cleo Kontoravdi, Paul S. Freemont,
Karen M. Polizzi … Cover Legend The cover image, by Lisa Goers et al., is based on the …
Karen M. Polizzi … Cover Legend The cover image, by Lisa Goers et al., is based on the …
Funding Belonging: The Relationship Between Higher Education Funding and Sense of Belonging
B Goers - 2023 - search.proquest.com
Sense of belonging is an important psychological and social factor for college students.
Students who report a strong sense of belonging to an institution are more likely to return the …
Students who report a strong sense of belonging to an institution are more likely to return the …