Co-culture techniques find myriad applications in biology for studying natural or synthetic
interactions between cell populations. Such techniques are of great importance in synthetic …

Engineered microbes are rapidly being developed for the delivery of therapeutic modalities
to sites of disease. Escherichia coli Nissle 1917 (EcN), a genetically tractable probiotic with a …

INTRODUCTION Detection of pathogens by the innate immune system is an essential first
step in successful host defense against infection. Pathogens are typically detected by germline…

Bacteria of the genus Shigella cause shigellosis, a severe gastrointestinal disease that is a
major cause of diarrhea-associated mortality in humans. Mice are highly resistant to Shigella …

Pyroptosis is an inflammatory form of cell death induced upon recognition of invading microbes.
During an infection, pyroptosis is enhanced in interferon-gamma-exposed cells via the …

Many high‐value added recombinant proteins, such as therapeutic glycoproteins, are produced
using mammalian cell cultures. In order to optimize the productivity of these cultures it is …

The use of biological entities as ‘sensors’ has long been of interest to engineers and
biologists. With recent advances in our ability to engineer biology, potential biosensors can be …

Mammalian cell cultures are used for production of biopharmaceuticals, eg monoclonal
antibodies. Only mammalian hybridoma cells contain the pathways for antibody production, but …

… Lisa Goers, Catherine Ainsworth, Cher Hui Goey, Cleo Kontoravdi, Paul S. Freemont,
Karen M. Polizzi … Cover Legend The cover image, by Lisa Goers et al., is based on the …

Sense of belonging is an important psychological and social factor for college students.
Students who report a strong sense of belonging to an institution are more likely to return the …