[PDF][PDF] Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity
…, R Williams, MR Chapman, LJ Levett, J Heaney… - Cell, 2021 - cell.com
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G
are suggestive of a selective advantage but may also be due to a random founder effect. We …
are suggestive of a selective advantage but may also be due to a random founder effect. We …
[HTML][HTML] Changes in symptomatology, reinfection, and transmissibility associated with the SARS-CoV-2 variant B. 1.1. 7: an ecological study
…, MR Chapman, LJ Levett, J Heaney… - The Lancet Public …, 2021 - thelancet.com
Background The SARS-CoV-2 variant B.1.1.7 was first identified in December, 2020, in
England. We aimed to investigate whether increases in the proportion of infections with this …
England. We aimed to investigate whether increases in the proportion of infections with this …
Extraction-free COVID-19 (SARS-CoV-2) diagnosis by RT-PCR to increase capacity for national testing programmes during a pandemic
PR Grant, MA Turner, GY Shin, E Nastouli, LJ Levett - BioRxiv, 2020 - biorxiv.org
Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) causes Coronavirus disease
2019 (COVID-19), a respiratory tract infection. The standard molecular diagnostic test is …
2019 (COVID-19), a respiratory tract infection. The standard molecular diagnostic test is …
[HTML][HTML] Investigation of hospital discharge cases and SARS-CoV-2 introduction into Lothian care homes
…, S Liggett, AH Beckett, MTG Holden, LJ Levett… - Journal of Hospital …, 2023 - Elsevier
Background The first epidemic wave of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
in Scotland resulted in high case numbers and mortality in care homes. In …
in Scotland resulted in high case numbers and mortality in care homes. In …
The QUTA activator and QUTR repressor proteins of Aspergillus nidulans interact to regulate transcription of the quinate utilization pathway genes
HK Lamb, GH Newton, LJ Levett, E Cairns… - …, 1996 - microbiologyresearch.org
Genetic evidence suggests that the activity of the native QUTA transcription activator protein
is negated by the action of the QUTR transcription repressor protein. When Aspergillus …
is negated by the action of the QUTR transcription repressor protein. When Aspergillus …
Complete discrepancy between abnormal fetal karyotypes predicted by QF‐PCR rapid testing and karyotyped cultured cells in a first‐trimester CVS
JJ Waters, S Walsh, LJ Levett, S Liddle… - Prenatal …, 2006 - Wiley Online Library
A chorion villus sample (CVS) biopsied at 11 weeks' gestation for raised nuchal translucency,
revealed monosomy X (presumptive 45,X karyotype) by QF‐PCR for rapid aneuploidy …
revealed monosomy X (presumptive 45,X karyotype) by QF‐PCR for rapid aneuploidy …
Comparative analysis of the QUTR transcription repressor protein and the three C-terminal domains of the pentafunctional AROM enzyme
…, JD MOORE, JH LAKEY, LJ LEVETT… - Biochemical …, 1996 - portlandpress.com
The AROM protein is a pentadomain protein catalysing steps two to six in the prechorismate
section of the shikimate pathway in microbial eukaryotes. On the basis of amino acid …
section of the shikimate pathway in microbial eukaryotes. On the basis of amino acid …
Identification of domains responsible for signal recognition and transduction within the QUTR transcription repressor protein
LJ LEVETT, SM SI-HOE, S LIDDLE… - Biochemical …, 2000 - portlandpress.com
QUTR (qutR-encoded transcription-repressing protein) is a multi-domain repressor protein
active in the signal-transduction pathway that regulates transcription of the quinic acid …
active in the signal-transduction pathway that regulates transcription of the quinic acid …
Kinetic analysis of the interaction between the QutA and QutR transcription‐regulating proteins
C Watts, SM Si‐Hoe, HK Lamb, LJ Levett… - Proteins: Structure …, 2002 - Wiley Online Library
The QutR protein is a multidomain repressor protein that interacts with the QutA activator
protein. Both proteins are active in the signal transduction pathway that regulates transcription …
protein. Both proteins are active in the signal transduction pathway that regulates transcription …
[HTML][HTML] Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort …
…, G Vernet, M Chapman, L Levett, J Heaney… - The Lancet Infectious …, 2022 - thelancet.com
Background The SARS-CoV-2 delta (B.1.617.2) variant was first detected in England in March,
2021. It has since rapidly become the predominant lineage, owing to high transmissibility. …
2021. It has since rapidly become the predominant lineage, owing to high transmissibility. …