Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes

…, EM Wigdor, EAW Slob, J Seidlitz, L Ronan… - Nature …, 2023 - nature.com
Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted …

[HTML][HTML] Obesity associated with increased brain age from midlife

L Ronan, AF Alexander-Bloch, K Wagstyl, S Farooqi… - Neurobiology of …, 2016 - Elsevier
Common mechanisms in aging and obesity are hypothesized to increase susceptibility to
neurodegeneration, however, direct evidence in support of this hypothesis is lacking. We …

Subtle in‐scanner motion biases automated measurement of brain anatomy from in vivo MRI

…, L Clasen, M Stockman, L Ronan… - Human brain …, 2016 - Wiley Online Library
While the potential for small amounts of motion in functional magnetic resonance imaging (fMRI)
scans to bias the results of functional neuroimaging studies is well appreciated, the …

Differential tangential expansion as a mechanism for cortical gyrification

L Ronan, N Voets, C Rua, A Alexander-Bloch… - Cerebral …, 2014 - academic.oup.com
Gyrification, the developmental buckling of the cortex, is not a random process—the forces
that mediate expansion do so in such a way as to generate consistent patterns of folds across …

[HTML][HTML] Cortical thickness gradients in structural hierarchies

K Wagstyl, L Ronan, IM Goodyer, PC Fletcher - Neuroimage, 2015 - Elsevier
MRI, enabling in vivo analysis of cortical morphology, offers a powerful tool in the assessment
of brain development and pathology. One of the most ubiquitous measures used—the …

Childhood obesity, cortical structure, and executive function in healthy children

L Ronan, A Alexander-Bloch, PC Fletcher - Cerebral cortex, 2020 - academic.oup.com
The development of executive function is linked to maturation of prefrontal cortex (PFC) in
childhood. Childhood obesity has been associated with changes in brain structure, particularly …

[HTML][HTML] The impact of the COVID-19 pandemic on mental health in the general population: a comparison between Germany and the UK

F Knolle, L Ronan, GK Murray - BMC psychology, 2021 - Springer
Background The COVID-19 pandemic has led to dramatic social and economic changes in
daily life. First studies report an impact on mental health of the general population showing …

[HTML][HTML] From genes to folds: a review of cortical gyrification theory

L Ronan, PC Fletcher - Brain Structure and Function, 2015 - Springer
Cortical gyrification is not a random process. Instead, the folds that develop are synonymous
with the functional organization of the cortex, and form patterns that are remarkably …

[HTML][HTML] Dispersion of functional gradients across the adult lifespan

RAI Bethlehem, C Paquola, J Seidlitz, L Ronan… - Neuroimage, 2020 - Elsevier
Ageing is commonly associated with changes to segregation and integration of functional
brain networks, but, in isolation, current network-based approaches struggle to elucidate …

[HTML][HTML] Increased body mass index is associated with specific regional alterations in brain structure

…, IS Farooqi, ET Bullmore, PJ Nathan, L Ronan… - International journal of …, 2016 - nature.com
Background: Although obesity is associated with structural changes in brain grey matter,
findings have been inconsistent and the precise nature of these changes is unclear. …