Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes
Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted …
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted …
[HTML][HTML] Obesity associated with increased brain age from midlife
L Ronan, AF Alexander-Bloch, K Wagstyl, S Farooqi… - Neurobiology of …, 2016 - Elsevier
Common mechanisms in aging and obesity are hypothesized to increase susceptibility to
neurodegeneration, however, direct evidence in support of this hypothesis is lacking. We …
neurodegeneration, however, direct evidence in support of this hypothesis is lacking. We …
Subtle in‐scanner motion biases automated measurement of brain anatomy from in vivo MRI
…, L Clasen, M Stockman, L Ronan… - Human brain …, 2016 - Wiley Online Library
While the potential for small amounts of motion in functional magnetic resonance imaging (fMRI)
scans to bias the results of functional neuroimaging studies is well appreciated, the …
scans to bias the results of functional neuroimaging studies is well appreciated, the …
Differential tangential expansion as a mechanism for cortical gyrification
L Ronan, N Voets, C Rua, A Alexander-Bloch… - Cerebral …, 2014 - academic.oup.com
Gyrification, the developmental buckling of the cortex, is not a random process—the forces
that mediate expansion do so in such a way as to generate consistent patterns of folds across …
that mediate expansion do so in such a way as to generate consistent patterns of folds across …
[HTML][HTML] Cortical thickness gradients in structural hierarchies
MRI, enabling in vivo analysis of cortical morphology, offers a powerful tool in the assessment
of brain development and pathology. One of the most ubiquitous measures used—the …
of brain development and pathology. One of the most ubiquitous measures used—the …
Childhood obesity, cortical structure, and executive function in healthy children
L Ronan, A Alexander-Bloch, PC Fletcher - Cerebral cortex, 2020 - academic.oup.com
The development of executive function is linked to maturation of prefrontal cortex (PFC) in
childhood. Childhood obesity has been associated with changes in brain structure, particularly …
childhood. Childhood obesity has been associated with changes in brain structure, particularly …
[HTML][HTML] The impact of the COVID-19 pandemic on mental health in the general population: a comparison between Germany and the UK
Background The COVID-19 pandemic has led to dramatic social and economic changes in
daily life. First studies report an impact on mental health of the general population showing …
daily life. First studies report an impact on mental health of the general population showing …
[HTML][HTML] From genes to folds: a review of cortical gyrification theory
L Ronan, PC Fletcher - Brain Structure and Function, 2015 - Springer
Cortical gyrification is not a random process. Instead, the folds that develop are synonymous
with the functional organization of the cortex, and form patterns that are remarkably …
with the functional organization of the cortex, and form patterns that are remarkably …
[HTML][HTML] Dispersion of functional gradients across the adult lifespan
Ageing is commonly associated with changes to segregation and integration of functional
brain networks, but, in isolation, current network-based approaches struggle to elucidate …
brain networks, but, in isolation, current network-based approaches struggle to elucidate …
[HTML][HTML] Increased body mass index is associated with specific regional alterations in brain structure
Background: Although obesity is associated with structural changes in brain grey matter,
findings have been inconsistent and the precise nature of these changes is unclear. …
findings have been inconsistent and the precise nature of these changes is unclear. …