Research on human brain development and neurological diseases is limited by the lack of
advanced experimental in vitro models that truly recapitulate the complexity of the human …

Modeling Parkinson’s disease (PD) using advanced experimental in vitro models is a
powerful tool to study disease mechanisms and to elucidate unexplored aspects of this …

Background and Aims: The biosimilar of Remicade®, CT-P13, recently entered the European
market. Clinical data on switching from Remicade® to CT-P13 in inflammatory bowel …

Background The etiology of Parkinson's disease (PD) is only partially understood despite the
fact that environmental causes, risk factors, and specific gene mutations are contributors to …

Background & Aims Colorectal neoplasia can still develop after colectomy for inflammatory
bowel disease. However, data on this risk are scare, and there have been few conclusive …

Background Limited data are available on long-term clinical outcomes regarding the switch
from Remicade ® to the infliximab biosimilar CT-P13 in inflammatory bowel disease (IBD) …

The study of human 3D cell culture models not only bridges the gap between traditional 2D
in vitro experiments and in vivo animal models, it also addresses processes that cannot be …

Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by the
loss of dopaminergic (DAergic) neurons in the substantia nigra and the gradual depletion of …

… , MUT35, and MUT70) were pulled for Drop-seq analysis as described in Smits et al.,
2020.… The presence of mesenchymal cells was also originally reported by Smits et al., 2020.…

Background and Aims There is paucity of data on safety and efficacy of anti-tumour necrosis
factor [TNF] in elderly inflammatory bowel disease [IBD] patients. We aimed to compare the …