This paper describes the current update on macromolecular model validation services that
are provided at the MolProbity website, emphasizing changes and additions since the …

Diffraction (X-ray, neutron and electron) and electron cryo-microscopy are powerful
methods to determine three-dimensional macromolecular structures, which are required to …

Traditionally, validation was considered to be a final gatekeeping function, but refinement is
smoother and results are better if model validation actively guides corrections throughout …

Vicinal disulfides between sequence-adjacent cysteine residues are very rare and rather
startling structural features which play a variety of functional roles. Typically discussed as an …

We find that the overall quite good methods used in the CryoEM Model Challenge could still
benefit greatly from several strategies for improving local conformations. Our assessments …

Cis-nonPro peptides, a very rare feature in protein structures, are of considerable importance
for two opposite reasons. On one hand, their genuine occurrences are mostly found at sites …

A new motif of three-dimensional (3D) protein structure is described, called the cis-Pro touch-turn.
In this four-residue, three-peptide motif, the central peptide is cis. Residue 2, which …

This paper describes the current update on macromolecular model validation services that
are provided at the MolProbity website, emphasizing changes and additions since the …

Many of the most exciting macromolecular structures are currently in the 2.5-4Å resolution
range--considered" low" for X-ray and" high" for cryoEM. For those techniques there are …

… Samantha O’Hanlon-Videau is thanked for aid in statistical analysis. We would like to thank
Philip Proteau (Oregon State University) and Lizbeth Videau (Duke University) for critical …