Lung cancer or pulmonary carcinoma is primarily derived from epithelial cells that are thin
and line on the alveolar surfaces of the lung for gas exchange. ANO1/TMEM16A, initially …

Overexpression of the Ca 2+ -activated chloride channel ANO1/TMEM16A is implicated in
tumorigenesis, and inhibition of ANO1 overexpression suppresses xenograft tumor growth …

Kindlin 2, as a focal adhesion protein, controls integrin activation and regulates Wnt signaling
in an integrin‐binding independent manner. However, the association of Kindlin 2 with …

Emerging evidence suggests that the cancer stem cells (CSCs) are key culprits of cancer
metastasis and drug resistance. Understanding mechanisms regulating the critical oncogenic …

ANO1, a calcium-activated chloride channel, has been reported to be amplified or
overexpressed in tissues of several cancers. However, reports on its roles in tumor progression …

Background: Patients with metastatic radioiodine-refractory papillary thyroid carcinoma (PTC)
have limited treatment options and a poor prognosis. There is an urgent need to develop …

Background Insulin-like growth factor 2 mRNA binding protein 3 (IMP3) is expressed in
metastatic and a subset of primary renal cell carcinoma (RCC). However, the role of IMP3 in RCC …

The heat shock protein 70 (Hsp70) is upregulated in response to stress and has been
implicated as a stress marker in temporal lobe epilepsy (TLE). However, whether Hsp70 plays a …

Kindlin-2, as a focal adhesion protein, has been found to regulate tumor progression. However,
the mechanism underlying Kindlin-2 regulation of tumor progression is largely unknown. …

Resistance to anticancer drugs is often observed in prostate cancer therapy. Kindlin-2 was
recently found overexpressed during cancer progression. In this study, we examined the …