[HTML][HTML] A Janus-faced bacterium: host-beneficial and-detrimental roles of Cutibacterium acnes

H Brüggemann, L Salar-Vidal, R Lood - Frontiers in Microbiology, 2021 - frontiersin.org
The bacterial species Cutibacterium acnes (formerly known as Propionibacterium acnes) is
tightly associated with humans. It is the dominant bacterium in sebaceous regions of the …

[HTML][HTML] SARS-CoV-2 mutant spectra at different depth levels reveal an overwhelming abundance of low frequency mutations

…, J Gómez, L Enjuanes, L Salar-Vidal… - Pathogens, 2022 - mdpi.com
Populations of RNA viruses are composed of complex and dynamic mixtures of variant genomes
that are termed mutant spectra or mutant clouds. This applies also to SARS-CoV-2, and …

Multicenter evaluation of the BIOFIRE Joint Infection Panel for the detection of bacteria, yeast, and AMR genes in synovial fluid samples

J Esteban, L Salar-Vidal, BH Schmitt… - Journal of clinical …, 2023 - Am Soc Microbiol
The bioMérieux BIOFIRE Joint Infection (JI) Panel is a multiplex in vitro diagnostic test for
the simultaneous and rapid (~1 h) detection of 39 potential pathogens and antimicrobial …

SARS-CoV-2 point mutation and deletion spectra and their association with different disease outcomes

…, J Gómez, L Enjuanes, L Salar-Vidal… - Microbiology …, 2022 - Am Soc Microbiol
Mutant spectra of RNA viruses are important to understand viral pathogenesis and response
to selective pressures. There is a need to characterize the complexity of mutant spectra in …

[HTML][HTML] Microbiological Characterization of Cutibacterium acnes Strains Isolated from Prosthetic Joint Infections

L Salar-Vidal, JJ Aguilera-Correa, H Brüggemann… - Antibiotics, 2022 - mdpi.com
Aims: This study aimed to characterize 79 Cutibacterium acnes strains isolated from prosthetic
joint infections (PJIs) originated from eight European hospitals. Methods: Isolates were …

Atypical mutational spectrum of SARS-CoV-2 replicating in the presence of ribavirin

…, C Ferrer-Orta, L Salar-Vidal… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
We report that ribavirin exerts an inhibitory and mutagenic activity on SARS-CoV-2-infecting
Vero cells, with a therapeutic index higher than 10. Deep sequencing analysis of the mutant …

[HTML][HTML] Molecular diagnosis of osteoarticular implant-associated infection: available techniques and how we can use them

L Salar-Vidal, Á Auńón, J Esteban - Prosthesis, 2022 - mdpi.com
Despite recent advances during the last few years, microbiological diagnosis of prosthetic
joint infections remains a challenge. Molecular biology techniques have been developed to try …

[HTML][HTML] SARS-CoV-2 mutant spectra as variant of concern nurseries: endless variation?

…, R Lorenzo-Redondo, L Salar-Vidal… - Frontiers in …, 2024 - frontiersin.org
Introduction SARS-CoV-2 isolates of a given clade may contain low frequency genomes that
encode amino acids or deletions which are typical of a different clade. Methods Here we …

[HTML][HTML] Genomic Analysis of Cutibacterium acnes Strains Isolated from Prosthetic Joint Infections

L Salar-Vidal, Y Achermann, JJ Aguilera-Correa… - Microorganisms, 2021 - mdpi.com
Cutibacterium acnes is a common cause of prosthetic joint infections (PJIs). The C. acnes
population can be divided into six main phylotypes (IA 1 , IA 2 , IB, IC, II and III) that are …

[HTML][HTML] Multicenter evaluation of BioFire JI panel related to improved microbiological diagnostics on acute osteoarticular infections

L Salar-Vidal, C Chaves, IT Dianzo-Delgado… - International Journal of …, 2023 - Elsevier
Microbiological diagnosis of osteoarticular infections (OI) is crucial for a successful treatment.
A prospective multicenter study including 262 synovial fluids with suspicion of acute OI was …