User profiles for Lluis Quintana-Murci
Lluis Quintana-MurciCollège de France and Institut Pasteur (CNRS UMR2000) Verified email at pasteur.fr Cited by 28786 |
Natural selection has driven population differentiation in modern humans
The considerable range of observed phenotypic variation in human populations may reflect,
in part, distinctive processes of natural selection and adaptation to variable environmental …
in part, distinctive processes of natural selection and adaptation to variable environmental …
From evolutionary genetics to human immunology: how selection shapes host defence genes
LB Barreiro, L Quintana-Murci - Nature Reviews Genetics, 2010 - nature.com
Pathogens have always been a major cause of human mortality, so they impose strong
selective pressure on the human genome. Data from population genetic studies, including …
selective pressure on the human genome. Data from population genetic studies, including …
[HTML][HTML] Evolutionary dynamics of human Toll-like receptors and their different contributions to host defense
Infectious diseases have been paramount among the threats to health and survival throughout
human evolutionary history. Natural selection is therefore expected to act strongly on host …
human evolutionary history. Natural selection is therefore expected to act strongly on host …
Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors
The quantification and characterization of circulating immune cells provide key indicators of
human health and disease. To identify the relative effects of environmental and genetic …
human health and disease. To identify the relative effects of environmental and genetic …
Genetic evidence of an early exit of Homo sapiens sapiens from Africa through eastern Africa
The out-of-Africa scenario 1 has hitherto provided little evidence for the precise route by
which modern humans left Africa. Two major routes of dispersal have been hypothesized: one …
which modern humans left Africa. Two major routes of dispersal have been hypothesized: one …
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
INTRODUCTION Interindividual clinical variability is vast in humans infected with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from silent infection to rapid …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from silent infection to rapid …
[HTML][HTML] Sexual inequality in tuberculosis
O Neyrolles, L Quintana-Murci - PLoS medicine, 2009 - journals.plos.org
… Lluis Quintana-Murci … Lluis Quintana-Murci … Copyright: © 2009 Neyrolles, Quintana-Murci.
This is an open-access article distributed under the terms of the Creative Commons …
This is an open-access article distributed under the terms of the Creative Commons …
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
…, CD Bustamante, JM Hombert, L Quintana-Murci - Science, 2017 - science.org
Bantu languages are spoken by about 310 million Africans, yet the genetic history of Bantu-speaking
populations remains largely unexplored. We generated genomic data for 1318 …
populations remains largely unexplored. We generated genomic data for 1318 …
[PDF][PDF] The matrilineal ancestry of Ashkenazi Jewry: portrait of a recent founder event
Both the extent and location of the maternal ancestral deme from which the Ashkenazi
Jewry arose remain obscure. Here, using complete sequences of the maternally inherited …
Jewry arose remain obscure. Here, using complete sequences of the maternally inherited …
[HTML][HTML] Genetic adaptation and Neandertal admixture shaped the immune system of human populations
Humans differ in the outcome that follows exposure to life-threatening pathogens, yet the
extent of population differences in immune responses and their genetic and evolutionary …
extent of population differences in immune responses and their genetic and evolutionary …