The Polycomb group protein EZH2 directly controls DNA methylation

E Viré, C Brenner, R Deplus, L Blanchon, M Fraga… - Nature, 2006 - nature.com
The establishment and maintenance of epigenetic gene silencing is fundamental to cell
determination and function 1 . The essential epigenetic systems involved in heritable repression …

Viral oncoproteins target the DNA methyltransferases

WA Burgers, L Blanchon, S Pradhan, Y De Launoit… - Oncogene, 2007 - nature.com
Small DNA tumour viruses have evolved a number of mechanisms to drive nondividing cells
into S phase. Virally encoded oncoproteins such as adenovirus E1A and human …

Rupture des membranes: physiopathologie, diagnostic, conséquences et prise en charge

L Blanchon, M Accoceberry, C Belville… - Journal de gynécologie …, 2013 - Elsevier
La rupture des membranes (RPM) est la résultante de contraintes physiques (étirement et
tension des membranes), de l’accentuation de l’apoptose et d’un déséquilibre entre la …

[HTML][HTML] Risk factors and outcomes of preterm premature rupture of membranes in a cohort of 6968 pregnant women prospectively recruited

D Bouvier, JC Forest, L Blanchon, E Bujold… - Journal of clinical …, 2019 - mdpi.com
We revisited risk factors and outcomes related to the preterm premature rupture of membranes
(PPROM). A total of 7866 pregnant women were recruited during 5 years at their first …

[HTML][HTML] Pathological Implications of Receptor for Advanced Glycation End-Product (AGER) Gene Polymorphism

…, R Blondonnet, C Gross, JM Constantin, L Blanchon… - Disease …, 2019 - hindawi.com
The receptor for advanced glycation end-products (RAGE) is a cell surface transmembrane
multiligand receptor, encoded by the AGER gene. RAGE presents many transcripts, is …

[HTML][HTML] Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a

R Deplus, L Blanchon, A Rajavelu, A Boukaba… - Cell reports, 2014 - cell.com
DNA methylation is a central epigenetic modification that is established by de novo DNA
methyltransferases. The mechanisms underlying the generation of genomic methylation …

Oxidative and antioxidative stress markers in dry eye disease: A systematic review and meta‐analysis

V Navel, V Sapin, F Henrioux, L Blanchon… - Acta …, 2022 - Wiley Online Library
Purpose To conduct a systematic review and meta‐analysis on the levels of oxidative stress
markers and antioxidants in dry eye disease (DED) compared with healthy subject. Method …

[HTML][HTML] A role for mesenchyme dynamics in mouse lung branching morphogenesis

P Blanc, K Coste, P Pouchin, JM Azaïs, L Blanchon… - PLoS …, 2012 - journals.plos.org
Mammalian airways are highly ramified tree-like structures that develop by the repetitive
branching of the lung epithelium into the surrounding mesenchyme through reciprocal …

Ontogeny of aquaporins in human fetal membranes

C Prat, L Blanchon, V Borel, D Gallot… - Biology of …, 2012 - academic.oup.com
It has been proposed that four members of the aquaporin family (AQPs 1, 3, 8, and 9) are
involved in the control of amniotic fluid (AF) homeostasis, as illustrated by their differential …

[HTML][HTML] Regulation of corneal keratin-12 gene expression by the human Kruppel-like transcription factor 6

F Chiambaretta, L Blanchon, B Rabier… - … & visual science, 2002 - iovs.arvojournals.org
purpose. The keratin-12 (K12) protein is essential for the integrity of the corneal epithelium.
This study was conducted to investigate the possible involvement of Krüppel-like factor 6 (…