Single-molecule DNA-mapping and whole-genome sequencing of individual cells
R Marie, JN Pedersen, L Bærlocher… - Proceedings of the …, 2018 - National Acad Sciences
To elucidate cellular diversity and clonal evolution in tissues and tumors, one must resolve
genomic heterogeneity in single cells. To this end, we have developed low-cost, mass-…
genomic heterogeneity in single cells. To this end, we have developed low-cost, mass-…
[HTML][HTML] Sequencing of human genomes extracted from single cancer cells isolated in a valveless microfluidic device
R Marie, M Pødenphant, K Koprowska, L Bærlocher… - Lab on a Chip, 2018 - pubs.rsc.org
Sequencing the genomes of individual cells enables the direct determination of genetic
heterogeneity amongst cells within a population. We have developed an injection-moulded …
heterogeneity amongst cells within a population. We have developed an injection-moulded …
Sequencing metrics of human genomes extracted from single cancer cells individually isolated in a valveless microfluidic device
R Marie, M Pødenphant, K Koprowska, L Bærlocher… - bioRxiv, 2018 - biorxiv.org
Sequencing the genomes of individual cells enables the direct determination of genetic
heterogeneity amongst cells within a population. We have developed an injection-moulded …
heterogeneity amongst cells within a population. We have developed an injection-moulded …
FINDEL: A Deep Learning Approach to Efficient Artifact Removal From Cancer Genomes
D Tan, P Zhou, S Zhang, VP Wong, J Zhang, E Long - bioRxiv, 2022 - biorxiv.org
Next-generation sequencing technologies have increased sequencing throughput by 100-1000
folds and subsequently reduced the cost of sequencing a human genome to …
folds and subsequently reduced the cost of sequencing a human genome to …
Scalable Methods for In Situ Genomics
AC Payne - 2021 - dspace.mit.edu
The maxim that biological structure determines function was inspired by the discovery of the
DNA double helix, yet mapping the structure of genomic DNA within a cell remains …
DNA double helix, yet mapping the structure of genomic DNA within a cell remains …
Microfluidic DNA sample preparation for long-read genomics
P Agrawal - 2020 - search.proquest.com
With the commercialization of genomics technologies, DNA sequencing has become an
affordable and accessible tool for innumerable biological advancements. The fast speed, low …
affordable and accessible tool for innumerable biological advancements. The fast speed, low …