Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

…, M Arendt, JE Krieger, M Kähönen, L Risch… - Nature …, 2017 - nature.com
Atrial fibrillation affects more than 33 million people worldwide and increases the risk of
stroke, heart failure, and death 1 , 2 . Fourteen genetic loci have been associated with atrial …

Effects of glucocorticoid immunosuppression on serum cystatin C concentrations in renal transplant patients

L Risch, R Herklotz, A Blumberg, AR Huber - Clinical chemistry, 2001 - academic.oup.com
tion was performed by adding 1 L of the post-PER to 9 L of formamide. We loaded each
sample on the ABI 310 genetic analyzer and tion was performed by adding 1 L of the post-PER …

[HTML][HTML] EDTA-anticoagulated whole blood for SARS-CoV-2 antibody testing by electrochemiluminescence immunoassay (ECLIA) and enzyme-linked immunosorbent …

M Kovac, L Risch, S Thiel, M Weber, K Grossmann… - Diagnostics, 2020 - mdpi.com
While lateral flow test formats can be utilized with whole blood and low sample volumes,
their diagnostic characteristics are inferior to immunoassays based on chemiluminescence …

Effect of volume loading with 1 liter intravenous infusions of 0.9% saline, 4% succinylated gelatine (Gelofusine) and 6% hydroxyethyl starch (Voluven) on blood …

…, C Wicks, QM Nunes, KL Ingram, L Risch… - Critical care …, 2010 - journals.lww.com
Objective: To study the changes in blood volume and hormones controlling sodium and
water homeostasis after infusions of 0.9% saline, Gelofusine (4% succinylated gelatin in 0.7% …

Severe coronavirus disease 2019 (COVID-19) is associated with elevated serum immunoglobulin (Ig) A and antiphospholipid IgA antibodies

O Hasan Ali, D Bomze, L Risch… - Clinical Infectious …, 2021 - academic.oup.com
Background Severe coronavirus disease 2019 (COVID-19) frequently entails complications
that bear similarities to autoimmune diseases. To date, there are little data on possible …

The complexity of kidney disease and diagnosing it–cystatin C, selective glomerular hypofiltration syndromes and proteome regulation

…, AJ Campos, M Risch, L Risch… - Journal of internal …, 2023 - Wiley Online Library
Estimation of kidney function is often part of daily clinical practice, mostly done by using the
endogenous glomerular filtration rate (GFR)‐markers creatinine or cystatin C. A …

Stability of hematological analytes depends on the hematology analyser used: a stability study with Bayer Advia 120, Beckman Coulter LH 750 and Sysmex XE 2100

…, L Risch, C Arbetsleitner, M Zerlauth, GM Risch… - Clinica chimica acta, 2008 - Elsevier
AIM: With the availability of newer hematology analysers, novel measurement techniques
are being introduced into daily routine. As analyte stability may differ according to the …

Rapid and accurate assessment of glomerular filtration rate in patients with renal transplants using serum cystatin C

L Risch, A Blumberg, A Huber - Nephrology Dialysis …, 1999 - academic.oup.com
Background. Assessment of renal function in patients with renal transplants is of great
importance. Various studies have reported cystatin C as an easily and rapidly assessable marker …

New alcohol-related genes suggest shared genetic mechanisms with neuropsychiatric disorders

…, J Auvinen, C Liu, M Männikkö, L Risch… - Nature human …, 2019 - nature.com
Excessive alcohol consumption is one of the main causes of death and disability worldwide.
Alcohol consumption is a heritable complex trait. Here we conducted a meta-analysis of …

Post-acute sequelae after severe acute respiratory syndrome coronavirus 2 infection by viral variant and vaccination status: A multicenter cross-sectional study

…, U Besold, A McGeer, L Risch… - Clinical Infectious …, 2023 - academic.oup.com
Background Disentangling the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants and vaccination on the occurrence of post-acute sequelae of SARS-…