PPARγ stimulation promotes mitochondrial biogenesis and prevents glucose deprivation-induced neuronal cell loss
G Miglio, AC Rosa, L Rattazzi, M Collino… - Neurochemistry …, 2009 - Elsevier
Peroxisome proliferator-activated receptor (PPAR)γ stimulation provides protection in several
models of neurological disorders, but the mechanisms underlying these effects remain to …
models of neurological disorders, but the mechanisms underlying these effects remain to …
'As above, so below'examining the interplay between emotion and the immune system
S Brod, L Rattazzi, G Piras, F D'Acquisto - Immunology, 2014 - Wiley Online Library
While the concept of a palpable relationship between our mental and physical well‐being is
certainly not new, it is only in the light of modern scientific research that we have begun to …
certainly not new, it is only in the light of modern scientific research that we have begun to …
[HTML][HTML] CD4+ but not CD8+ T cells revert the impaired emotional behavior of immunocompromised RAG-1-deficient mice
L Rattazzi, G Piras, M Ono, R Deacon… - Translational …, 2013 - nature.com
An imbalanced immune system has long been known to influence a variety of mood disorders
including anxiety, obsessive-compulsive disorders and depression. In this study, we …
including anxiety, obsessive-compulsive disorders and depression. In this study, we …
The subtypes of peroxisome proliferator‐activated receptors expressed by human podocytes and their role in decreasing podocyte injury
G Miglio, AC Rosa, L Rattazzi, C Grange… - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE Peroxisome proliferator‐activated receptors (PPARs) are
ligand‐activated transcription factors, and three subtypes (α, β and γ) have been identified. …
ligand‐activated transcription factors, and three subtypes (α, β and γ) have been identified. …
[HTML][HTML] Formyl peptide receptor as a novel therapeutic target for anxiety-related disorders
I Gallo, L Rattazzi, G Piras, T Gobbetti, E Panza… - PloS one, 2014 - journals.plos.org
Formyl peptide receptors (FPR) belong to a family of sensors of the immune system that detect
microbe-associated molecules and inform various cellular and sensorial mechanisms to …
microbe-associated molecules and inform various cellular and sensorial mechanisms to …
[HTML][HTML] Impaired sense of smell and altered olfactory system in RAG-1−∕− immunodeficient mice
L Rattazzi, A Cariboni, R Poojara… - Frontiers in …, 2015 - frontiersin.org
Immune deficiencies are often associated with a number of physical manifestations including
loss of sense of smell and an increased level of anxiety. We have previously shown that T …
loss of sense of smell and an increased level of anxiety. We have previously shown that T …
[HTML][HTML] Massage-like stroking boosts the immune system in mice
B Major, L Rattazzi, S Brod, I Pilipović, G Leposavić… - Scientific reports, 2015 - nature.com
Recent clinical evidence suggests that the therapeutic effect of massage involves the immune
system and that this can be exploited as an adjunct therapy together with standard drug-…
system and that this can be exploited as an adjunct therapy together with standard drug-…
Angiotensin II induces tumor necrosis factor-α expression and release from cultured human podocytes
AC Rosa, L Rattazzi, G Miglio, M Collino… - Inflammation …, 2012 - Springer
Objective High levels of both angiotensin (Ang) II and tumor necrosis factor (TNF)-α have been
implicated in the pathogenesis of glomerular injury by affecting podocytes. The aim of this …
implicated in the pathogenesis of glomerular injury by affecting podocytes. The aim of this …
PPARγ stimulation promotes neurite outgrowth in SH-SY5Y human neuroblastoma cells
G Miglio, L Rattazzi, AC Rosa, R Fantozzi - Neuroscience Letters, 2009 - Elsevier
Several evidences indicate that PPARγ stimulation promotes neuronal differentiation. However,
to date, no data describe the effects of PPARγ agonists on neurite outgrowth. Here we …
to date, no data describe the effects of PPARγ agonists on neurite outgrowth. Here we …
Pro-inflammatory and pathogenic properties of Annexin-A1: the whole is greater than the sum of its parts
F D'Acquisto, G Piras, L Rattazzi - Biochemical pharmacology, 2013 - Elsevier
According to Aristotle, “The whole is greater than the sum of its parts” and yet, although a
long time has passed still, we seem to struggle to accept this universal concept. Searching in …
long time has passed still, we seem to struggle to accept this universal concept. Searching in …