Glial cells play a critical role in maintaining homeostatic ion concentration gradients. Salt-inducible
kinase 3 (SIK3) regulates a gene expression program that controls K + buffering in …

The suprachiasmatic nucleus (SCN) synchronizes circadian rhythms in behavior and physiology
to the external light cycle, but the mechanisms by which this occurs are unclear. As the …

Glia modulate neuronal excitability and seizure sensitivity by maintaining potassium and
water homeostasis. A salt inducible kinase 3 (SIK3)-regulated gene expression program …

K+ homeostasis is important for maintaining healthy, physiological levels of neuronal activity.
Glial cells play a central role in maintaining homeostatic ion gradients. In previous work …

Circadian (~24 h) rhythms influence nearly all aspects of physiology, including sleep/wake,
metabolism, and hormone release. The suprachiasmatic nucleus (SCN) synchronizes these …

Purpose: Juvenile Neuronal Ceroid Lipofuscinosis (JNCL), or Batten disease, is a lysosomal
storage disorder caused by mutations in CLN3 that cause blindness, central nervous …

A fundamental question in neuroscience is: how does a sensory system optimize detection
of behaviorally relevant stimuli, when those stimuli and the sensory environment are …

In a rollover lottery, buyers pick their own numbers, and a jackpot not won adds to the next
draw. We develop an equilibrium model of this lottery, since it is a major source of government …

Gene regulation allows for the quantitative control of gene expression. Gene regulation is a
complex process encoded through cis-regulatory sequences, short DNA sequences …

… Additionally, I’ve also had the opportunity to work with two very talented rotational students:
Lorenzo Lones and Travis Tabor. Thanks for bearing with me and working very hard during …