Most single point mutations destabilize folded proteins. Mutations that stabilize a protein
typically only have a small effect and multiple mutations are often needed to substantially …

Strategies for investigating and optimizing the expression and folding of proteins for
biotechnological and pharmaceutical purposes are in high demand. Here, we describe a dual-…

Designing proteins with stability higher than the wild type is not always straightforward. Methods
for rational design often fail to predict stabilizing mutations and the effect of substituting …

Most single point mutations destabilize folded proteins. Mutations that stabilize a protein
typically only have a small effect and multiple mutations are often needed to substantially …

Background Capsid virus-like particles (cVLP) have proven safe and immunogenic and can
be a versatile platform to counter pandemics. We aimed to clinically test a modular cVLP …

Die vorliegende Masterarbeit trägt den Titel: Regionale und kulturelle Unterschiede
zwischen Nordund Süddeutschland aus dänischer Sicht. Das Ziel dieser Arbeit ist durch eine …

Ca 2+ /calmodulin-dependent protein kinase II alpha (CaMKIIα) is a brain-relevant kinase
and an emerging drug target for ischemic stroke and neurodegenerative disorders. Despite …

γHydroxybutyric acid (GHB) analogs are small molecules that bind competitively to a specific
cavity in the oligomeric CaMKIIα hub domain. Binding affects conformation and stability of …

Cell-free protein synthesis (CFPS) systems offer a versatile platform for a wide range of
applications. However, the traditional methods for detecting proteins synthesized in CFPS, such …

… Mange af dem skal jo netop fremstå som elegante, dekorative og overfladiske - Louise de
(… , fremhæver Ophuls attraktionsværdien ved et forlæg af Louise de Vilmorin Histoire d’Aimer […