Prolonged estrogen deprivation triggers a broad immunosuppressive phenotype in breast cancer cells
…, B Porebski, M Häggblad, L Lidemalm… - Molecular …, 2022 - Wiley Online Library
Among others, expression levels of programmed cell death 1 ligand 1 (PD‐L1) have been
explored as biomarkers of the response to immune checkpoint inhibitors in cancer therapy. …
explored as biomarkers of the response to immune checkpoint inhibitors in cancer therapy. …
[PDF][PDF] A chemical screen identifies compounds limiting the toxicity of C9ORF72 dipeptide repeats
…, M Häggblad, L Bräutigam, V Lafarga, L Lidemalm… - Cell chemical …, 2019 - cell.com
The expansion of GGGGCC repeats within the first intron of C9ORF72 constitutes the most
common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). …
common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). …
New regulators of the tetracycline‐inducible gene expression system identified by chemical and genetic screens
The tetracycline repressor (tetR)‐regulated system is a widely used tool to specifically
control gene expression in mammalian cells. Based on this system, we generated a human …
control gene expression in mammalian cells. Based on this system, we generated a human …
Baseline dasabuvir resistance in Hepatitis C virus from the genotypes 1, 2 and 3 and modeling of the NS5B-dasabuvir complex by the in silico approach
…, M Kjellin, N Kameli, L Lidemalm… - Infection Ecology & …, 2018 - Taylor & Francis
… Louise Lidemalm Louise Lidemalm did her BSc at Swedish university of agricultural sciences
and her Master studies at Uppsala University and she conducted her master project 2015 …
and her Master studies at Uppsala University and she conducted her master project 2015 …
Estrogen deprivation triggers an immunosuppressive phenotype in breast cancer cells
…, K Tschapalda, B Porebski, M Häggblad, L Lidemalm… - BioRxiv, 2019 - biorxiv.org
Estrogen receptor (ER)-positive breast tumors are routinely treated with estrogen-depriving
therapies. Despite their effectiveness, patients often progress into a more aggressive form of …
therapies. Despite their effectiveness, patients often progress into a more aggressive form of …
Discovery of a novel inhibitor of macropinocytosis with antiviral activity
…, A Corman, M Haraldsson, M Barz, L Lidemalm… - bioRxiv, 2023 - biorxiv.org
Several viruses hijack various forms of endocytosis in order to infect host cells. Here, we
report the discovery of a new molecule with antiviral properties that we named virapinib, which …
report the discovery of a new molecule with antiviral properties that we named virapinib, which …
The anti-leprosy drug clofazimine reduces polyQ toxicity through activation of PPARγ
X Li, I Hernandez, M Häggblad, L Lidemalm… - bioRxiv, 2023 - biorxiv.org
PolyQ diseases are autosomal dominant neurodegenerative disorders caused by the expansion
of CAG repeats. While of slow progression, these diseases are ultimately fatal and lack …
of CAG repeats. While of slow progression, these diseases are ultimately fatal and lack …
Chemical and genetic screens identify new regulators of tetracycline-inducible gene expression system in mammalian cells
The tetracycline repressor (tetR)-regulated system is a widely used tool to specifically
control gene expression in mammalian cells. Based on this system, we generated a human …
control gene expression in mammalian cells. Based on this system, we generated a human …
Characterisation of Wheat dwarf virus isolates from the vector Psammotettix alienus
L Lidemalm - 2014 - stud.epsilon.slu.se
Wheat dwarf disease caused by Wheat dwarf virus (WDV) can cause a lot of damage in
wheat fields by reduction of yield. WDV belongs to the genus Mastrevirus in the family of …
wheat fields by reduction of yield. WDV belongs to the genus Mastrevirus in the family of …
Discovery of a novel inhibitor of macropinocytosis with antiviral activity (preprint)
…, A Corman, M Haraldsson, M Barz, L Lidemalm… - 2023 - pesquisa.bvsalud.org
Several viruses hijack various forms of endocytosis in order to infect host cells. Here, we
report the discovery of a new molecule with antiviral properties that we named virapinib, which …
report the discovery of a new molecule with antiviral properties that we named virapinib, which …