User profiles for Louise Uoselis
 | Louise UoselisWalter and Eliza Hall Institute of Medical Research Verified email at wehi.edu.au Cited by 258 |
[HTML][HTML] LC3/GABARAPs drive ubiquitin-independent recruitment of Optineurin and NDP52 to amplify mitophagy
Current models of selective autophagy dictate that autophagy receptors, including Optineurin
and NDP52, link cargo to autophagosomal membranes. This is thought to occur via …
and NDP52, link cargo to autophagosomal membranes. This is thought to occur via …
[PDF][PDF] Mitochondrial degradation: Mitophagy and beyond
Mitochondria are central hubs of cellular metabolism that also play key roles in signaling and
disease. It is therefore fundamentally important that mitochondrial quality and activity are …
disease. It is therefore fundamentally important that mitochondrial quality and activity are …
[PDF][PDF] ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system
The sequestration of damaged mitochondria within double-membrane structures termed
autophagosomes is a key step of PINK1/Parkin mitophagy. The ATG4 family of proteases are …
autophagosomes is a key step of PINK1/Parkin mitophagy. The ATG4 family of proteases are …
Temporal landscape of mitochondrial proteostasis governed by the UPRmt
L Uoselis, R Lindblom, WK Lam, CJ Küng… - Science …, 2023 - science.org
Breakdown of mitochondrial proteostasis activates quality control pathways including the
mitochondrial unfolded protein response (UPR mt ) and PINK1/Parkin mitophagy. However, …
mitochondrial unfolded protein response (UPR mt ) and PINK1/Parkin mitophagy. However, …
[PDF][PDF] Preparation of soluble and insoluble mitochondrial protein fractions for mass spectrometry analysis
L Uoselis - 2023 - protocols.io
… Louise Uoselis … Protocol Citation: Louise Uoselis 2023. Preparation of soluble and
insoluble mitochondrial protein fractions for mass spectrometry analysis. …
insoluble mitochondrial protein fractions for mass spectrometry analysis. …
Preparation of soluble and insoluble mitochondrial protein fractions for immunoblotting
L Uoselis - 2023 - protocols.io
6 Using a pipette, carefully remove 14.24 µL of the supernatant (representing 95% of the lysis
volume) and place this sample into a clean microfuge tube on ice, being sure not to disturb …
volume) and place this sample into a clean microfuge tube on ice, being sure not to disturb …
Generation of stable cell lines using viral infection
L Uoselis - 2023 - protocols.io
Protocol for generation and precipitation of retrovirus, and infection of HeLa cells to generate
stable cell lines.
stable cell lines.
Mitophagy induction using Difereprone
L Uoselis - 2023 - protocols.io
… Louise Uoselis … Louise Uoselis Louise Uoselis …
Mitochondrial damage control: delineating the mechanisms of mitochondrial repair
LM UOSELIS - 2022 - bridges.monash.edu
Mitochondrial function is essential for our health. The mitochondrial quality control
machinery identifies and remedies dysfunctional mitochondria to protect the health of our …
machinery identifies and remedies dysfunctional mitochondria to protect the health of our …
Mitophagy induction using Oligomycin/Antimycin A
L Uoselis - 2023 - protocols.io
… Louise Uoselis … Louise Uoselis Louise Uoselis …