User profiles for Luís Maurício T. R. Lima

Luis Mauricio TR Lima

Professor of Structural Biology, Federal University of Rio de Janeiro - UFRJ - Brazil
Verified email at UFRJ.BR
Cited by 3485

Green production of microalgae-based silver chloride nanoparticles with antimicrobial activity against pathogenic bacteria

…, ME ConzFerreira, LMTR Lima… - Enzyme and Microbial …, 2017 - Elsevier
Silver nanoparticles are powerful antimicrobial agents. Here, the synthesis of silver chloride
nanoparticles (AgCl-NPs) was consistently evidenced from a commercially valuable …

Intriguing nucleic-acid-binding features of mammalian prion protein

JL Silva, LMTR Lima, D Foguel, Y Cordeiro - Trends in biochemical …, 2008 - cell.com
In transmissible spongiform encephalopathies, the infectious material consists chiefly of a
protein, the scrapie prion protein PrP Sc , that carries no genetic coding material; however, …

Yeast-derived biosynthesis of silver/silver chloride nanoparticles and their antiproliferative activity against bacteria

…, N Müller, S Frasés, R Almeida-Paes, LMTR Lima… - Rsc Advances, 2016 - pubs.rsc.org
Here, we provide the first evidence of yeast strains assisted Ag/AgCl-NPs production in vitro.
The formed nanoparticles were characterized by spectroscopic and electron microscopy …

[HTML][HTML] Hydration and packing effects on prion folding and β-sheet conversion: High pressure spectroscopy and pressure perturbation calorimetry studies

Y Cordeiro, J Kraineva, R Ravindra, LMTR Lima… - Journal of Biological …, 2004 - ASBMB
The main hypothesis for prion diseases proposes that the cellular protein (PrP C ) can be
altered into a misfolded, β-sheet-rich isoform (PrP Sc ), which undergoes aggregation and …

Pressure induces folding intermediates that are crucial for protein–DNA recognition and virus assembly

JL Silva, AC Oliveira, AMO Gomes, LMTR Lima… - … et Biophysica Acta (BBA …, 2002 - Elsevier
Protein–nucleic acid interactions are crucial for a variety of fundamental biological processes
such as replication, transcription, restriction, translation and virus assembly. The molecular …

Amyloidogenesis of the amylin analogue pramlintide

DC da Silva, GN Fontes, LCS Erthal, LMTR Lima - Biophysical chemistry, 2016 - Elsevier
… Fontes b , Luiza CS Erthal a , Luís Maurício TR Lima a b c … Luis Mauricio TR Lima, is
applicant of patents regarding controlled release of … Girad-Dias, KR de Miranda, LMTR Lima

[HTML][HTML] Flavonoid interactions with human transthyretin: combined structural and thermodynamic analysis

DBB Trivella, CV dos Reis, LMTR Lima… - Journal of structural …, 2012 - Elsevier
Transthyretin (TTR) is a carrier protein involved in human amyloidosis. The development of
small molecules that may act as TTR amyloid inhibitors is a promising strategy to treat these …

Ligand binding and hydration in protein misfolding: insights from studies of prion and p53 tumor suppressor proteins

…, MPB Gomes, APA Bom, LMTR Lima… - Accounts of chemical …, 2010 - ACS Publications
Protein misfolding has been implicated in a large number of diseases termed protein- folding
disorders (PFDs), which include Alzheimer’s disease, Parkinson’s disease, transmissible …

[HTML][HTML] Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: implications to tetramer stability and ligand …

…, CA Montanari, JW Kelly, LMTR Lima… - Journal of structural …, 2010 - Elsevier
Transthyretin (TTR) is a tetrameric β-sheet-rich transporter protein directly involved in human
amyloid diseases. It was recently found that the isoflavone genistein (GEN) potently inhibits …

[HTML][HTML] Modulation of prion protein oligomerization, aggregation, and β-sheet conversion by 4, 4′-dianilino-1, 1′-binaphthyl-5, 5′-sulfonate (bis-ANS)

Y Cordeiro, LMTR Lima, MPB Gomes, D Foguel… - Journal of Biological …, 2004 - ASBMB
The prion protein (PrP) is the major agent implicated in the diseases known as transmissible
spongiform encephalopathies. The onset of transmissible spongiform encephalopathy is …