A comprehensive evaluation of normalization methods for Illumina high-throughput RNA sequencing data analysis

…, J Estelle, G Guernec, B Jagla, L Jouneau… - Briefings in …, 2013 - academic.oup.com
During the last 3 years, a number of approaches for the normalization of RNA sequencing
data have emerged in the literature, differing both in the type of bias adjustment and in the …

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

…, VD Dang, Y Jaimes, C Daridon, R Li, L Jouneau… - Nature, 2014 - nature.com
B lymphocytes have critical roles as positive and negative regulators of immunity. Their
inhibitory function has been associated primarily with interleukin 10 (IL-10) because B-cell-…

[PDF][PDF] LAG-3 inhibitory receptor expression identifies immunosuppressive natural regulatory plasma cells

…, V Flühler, I Sakwa, U Stervbo, S Ries, L Jouneau… - Immunity, 2018 - cell.com
B lymphocytes can suppress immunity through interleukin (IL)-10 production in infectious,
autoimmune, and malignant diseases. Here, we have identified a natural plasma cell subset …

[HTML][HTML] Maternal diets trigger sex-specific divergent trajectories of gene expression and epigenetic systems in mouse placenta

A Gabory, L Ferry, I Fajardy, L Jouneau, JD Gothié… - PloS one, 2012 - journals.plos.org
Males and females responses to gestational overnutrition set the stage for subsequent sex-specific
differences in adult onset non communicable diseases. Placenta, as a widely …

[HTML][HTML] Teleost fish mount complex clonal IgM and IgT responses in spleen upon systemic viral infection

R Castro, L Jouneau, HP Pham, O Bouchez… - PLoS …, 2013 - journals.plos.org
Upon infection, B-lymphocytes expressing antibodies specific for the intruding pathogen
develop clonal responses triggered by pathogen recognition via the B-cell receptor. The …

[HTML][HTML] Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfish

P Boudinot, LM van Der Aa, L Jouneau, L Du Pasquier… - PloS one, 2011 - journals.plos.org
Tripartite motif proteins (TRIM) constitute a large family of proteins containing a RING-Bbox-Coiled
Coil motif followed by different C-terminal domains. Involved in ubiquitination, TRIM …

Restricting nonclassical MHC genes coevolve with TRAV genes used by innate-like T cells in mammals

P Boudinot, S Mondot, L Jouneau… - Proceedings of the …, 2016 - National Acad Sciences
Whereas major histocompatibility class-1 (MH1) proteins present peptides to T cells
displaying a large T-cell receptor (TR) repertoire, MH1Like proteins, such as CD1D and MR1, …

Naive and primed murine pluripotent stem cells have distinct miRNA expression profiles

A Jouneau, C Ciaudo, O Sismeiro, V Brochard… - Rna, 2012 - rnajournal.cshlp.org
Over the last years, the microRNA (miRNA) pathway has emerged as a key component of
the regulatory network of pluripotency. Although clearly distinct states of pluripotency have …

Existence of CD8α-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species

…, T Andrieu, K Crozat, L Jouneau… - The Journal of …, 2010 - journals.aai.org
The mouse lymphoid organ-resident CD8α+ dendritic cell (DC) subset is specialized in Ag
presentation to CD8+ T cells. Recent evidence shows that mouse nonlymphoid tissue CD103…

B cells producing type I IFN modulate macrophage polarization in tuberculosis

…, A Colom, I Mercier, L Tailleux, L Jouneau… - American journal of …, 2018 - atsjournals.org
Rationale: In addition to their well-known function as antibody-producing cells, B lymphocytes
can markedly influence the course of infectious or noninfectious diseases via antibody-…